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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP2 All Species: 43.03
Human Site: Y112 Identified Species: 63.11
UniProt: P26885 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26885 NP_001128680.1 142 15649 Y112 V I P S E L G Y G E R G A P P
Chimpanzee Pan troglodytes XP_001164246 142 15597 Y112 V I P S E L G Y G E R G A P P
Rhesus Macaque Macaca mulatta XP_001115120 142 15569 Y112 V I P S E L G Y G E R G A P P
Dog Lupus familis XP_853295 161 17525 Y131 V I P S E L G Y G E R G A P P
Cat Felis silvestris
Mouse Mus musculus P45878 140 15325 Y110 V I P S E L G Y G E R G A P P
Rat Rattus norvegicus Q62658 108 11904 P79 R A K L I I S P D Y A Y G A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001079493 141 15706 Y111 V I P S E L G Y G D R G A P P
Zebra Danio Brachydanio rerio NP_001004677 126 13669 K97 L G M C E G E K R K L V I P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48375 108 11648 P79 R A K L I C S P D Y A Y G S R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502056 139 15453 Y108 T I P P H L G Y G E R G A P P
Sea Urchin Strong. purpuratus XP_785999 142 15573 Y110 V I P S N L G Y G D R G S P P
Poplar Tree Populus trichocarpa XP_002301808 153 16028 Y114 K I P A K L G Y G E Q G S P P
Maize Zea mays NP_001148416 148 15769 Y113 K I P S K L G Y G P Q G S P P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38936 163 17640 Y115 K I P A K L G Y G E Q G S P P
Baker's Yeast Sacchar. cerevisiae P32472 135 14468 A106 L Q I P S S L A Y G E R G V P
Red Bread Mold Neurospora crassa O60046 217 22896 G104 L T V P P S Y G Y G Q R S I G
Conservation
Percent
Protein Identity: 100 98.5 98.5 85 N.A. 95 38 N.A. N.A. N.A. 77.4 71.1 N.A. 36.6 N.A. 61.9 65.4
Protein Similarity: 100 99.3 99.3 86.3 N.A. 97.8 52.8 N.A. N.A. N.A. 88 80.9 N.A. 52.8 N.A. 73.2 80.2
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. N.A. N.A. 93.3 13.3 N.A. 0 N.A. 80 80
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. N.A. N.A. 100 26.6 N.A. 0 N.A. 80 93.3
Percent
Protein Identity: 48.3 52.7 N.A. 45.4 45.7 31.8
Protein Similarity: 67.9 66.8 N.A. 60.7 59.8 44.7
P-Site Identity: 66.6 66.6 N.A. 66.6 6.6 0
P-Site Similarity: 93.3 86.6 N.A. 93.3 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 13 0 0 0 7 0 0 13 0 44 7 0 % A
% Cys: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 13 13 0 0 0 0 0 % D
% Glu: 0 0 0 0 44 0 7 0 0 50 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 0 7 69 7 69 13 0 69 19 0 7 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 69 7 0 13 7 0 0 0 0 0 0 7 7 0 % I
% Lys: 19 0 13 0 19 0 0 7 0 7 0 0 0 0 0 % K
% Leu: 19 0 0 13 0 69 7 0 0 0 7 0 0 0 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 69 19 7 0 0 13 0 7 0 0 0 75 75 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 25 0 0 0 0 % Q
% Arg: 13 0 0 0 0 0 0 0 7 0 50 13 0 0 7 % R
% Ser: 0 0 0 50 7 13 13 0 0 0 0 0 32 7 7 % S
% Thr: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % T
% Val: 44 0 7 0 0 0 0 0 0 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 69 13 13 0 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _