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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MST1 All Species: 12.12
Human Site: S643 Identified Species: 26.67
UniProt: P26927 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26927 NP_066278.3 711 80320 S643 H R G R V R E S E M C T E G L
Chimpanzee Pan troglodytes XP_519174 728 83101 S655 G K V T L N E S E I C A G A E
Rhesus Macaque Macaca mulatta P12545 810 90237 K740 E F L N G T V K T T E L C A G
Dog Lupus familis XP_541884 712 80219 N644 H R G R I R E N E M C T E G L
Cat Felis silvestris
Mouse Mus musculus P26928 716 80570 S648 Y R G H I Q E S E I C T Q G L
Rat Rattus norvegicus P17945 728 82887 N656 H Q G K V T L N E S E L C A G
Wallaby Macropus eugenll O18783 806 90963 K736 E Y L N G R V K S T E L C A G
Platypus Ornith. anatinus XP_001506451 860 97099 T674 H K G K I T L T E S E I C A G
Chicken Gallus gallus NP_990544 704 79323 S636 L R G R L K E S E L C T A P L
Frog Xenopus laevis NP_001079527 717 81999 V646 Y R S Q R N K V L D N E M C T
Zebra Danio Brachydanio rerio NP_694512 709 81253 N641 F K G R V R E N E M C T M A F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.6 38.6 87 N.A. 79.7 43.1 36.4 35.1 62.3 59.5 56.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57.6 50.9 91.9 N.A. 87.7 57.8 50.8 48 75.1 74 71.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 0 86.6 N.A. 60 26.6 6.6 20 60 6.6 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 46.6 0 100 N.A. 93.3 46.6 6.6 46.6 80 26.6 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 10 55 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 55 0 37 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 19 0 0 0 0 0 55 0 73 0 37 10 19 0 10 % E
% Phe: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 0 64 0 19 0 0 0 0 0 0 0 10 28 37 % G
% His: 37 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 28 0 0 0 0 19 0 10 0 0 0 % I
% Lys: 0 28 0 19 0 10 10 19 0 0 0 0 0 0 0 % K
% Leu: 10 0 19 0 19 0 19 0 10 10 0 28 0 0 37 % L
% Met: 0 0 0 0 0 0 0 0 0 28 0 0 19 0 0 % M
% Asn: 0 0 0 19 0 19 0 28 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 10 0 10 0 10 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 46 0 37 10 37 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 0 37 10 19 0 0 0 0 0 % S
% Thr: 0 0 0 10 0 28 0 10 10 19 0 46 0 0 10 % T
% Val: 0 0 10 0 28 0 19 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _