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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MST1
All Species:
31.82
Human Site:
Y106
Identified Species:
70
UniProt:
P26927
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26927
NP_066278.3
711
80320
Y106
D
L
F
Q
K
K
D
Y
V
R
T
C
I
M
N
Chimpanzee
Pan troglodytes
XP_519174
728
83101
Y124
D
L
Y
E
N
K
D
Y
I
R
N
C
I
I
G
Rhesus Macaque
Macaca mulatta
P12545
810
90237
Y99
V
L
F
E
K
K
V
Y
L
S
E
C
K
T
G
Dog
Lupus familis
XP_541884
712
80219
Y107
D
L
F
Q
K
K
D
Y
V
R
T
C
I
T
D
Cat
Felis silvestris
Mouse
Mus musculus
P26928
716
80570
Y106
H
L
F
Q
K
K
D
Y
V
R
T
C
I
M
D
Rat
Rattus norvegicus
P17945
728
82887
Y125
D
L
Y
E
N
K
D
Y
I
R
N
C
I
I
G
Wallaby
Macropus eugenll
O18783
806
90963
Y99
V
L
F
E
K
R
I
Y
L
S
D
C
K
S
G
Platypus
Ornith. anatinus
XP_001506451
860
97099
Y141
D
L
Y
E
K
K
D
Y
I
R
N
C
I
I
G
Chicken
Gallus gallus
NP_990544
704
79323
F104
D
L
Y
Q
K
K
D
F
L
R
E
C
I
V
A
Frog
Xenopus laevis
NP_001079527
717
81999
Y115
D
L
Y
Q
K
K
D
Y
I
R
D
C
V
V
G
Zebra Danio
Brachydanio rerio
NP_694512
709
81253
Y107
D
L
Y
E
M
K
V
Y
V
R
K
C
I
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.6
38.6
87
N.A.
79.7
43.1
36.4
35.1
62.3
59.5
56.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57.6
50.9
91.9
N.A.
87.7
57.8
50.8
48
75.1
74
71.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
40
86.6
N.A.
86.6
53.3
33.3
60
60
60
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
53.3
93.3
N.A.
93.3
80
53.3
86.6
86.6
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% C
% Asp:
73
0
0
0
0
0
73
0
0
0
19
0
0
0
19
% D
% Glu:
0
0
0
55
0
0
0
0
0
0
19
0
0
0
0
% E
% Phe:
0
0
46
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
37
0
0
0
73
28
0
% I
% Lys:
0
0
0
0
73
91
0
0
0
0
10
0
19
0
0
% K
% Leu:
0
100
0
0
0
0
0
0
28
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
19
0
% M
% Asn:
0
0
0
0
19
0
0
0
0
0
28
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
82
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
19
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
28
0
0
19
0
% T
% Val:
19
0
0
0
0
0
19
0
37
0
0
0
10
28
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
55
0
0
0
0
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _