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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNTFR All Species: 12.73
Human Site: S342 Identified Species: 40
UniProt: P26992 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26992 NP_001833.1 372 40633 S342 C D P G E L G S G G G P S A P
Chimpanzee Pan troglodytes XP_528588 380 41177 S350 C D P G E L G S G G G P S A P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_855105 468 51305 L354 D I A N A T S L P V Q D S S S
Cat Felis silvestris
Mouse Mus musculus O88507 372 40783 S342 C D P G E L G S G G G P S I L
Rat Rattus norvegicus Q08406 372 40804 S342 C D P G E L S S G G G P S I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518281 210 22780 V181 E V R V E L S V R A E I C P V
Chicken Gallus gallus P51641 362 40289 T330 S F M P P P T T K I C D K G A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001091712 357 40158 A328 T P G P P S A A P R V G E P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 N.A. 26.2 N.A. 95.1 94 N.A. 30.1 69 N.A. 52.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 76.3 N.A. 38.8 N.A. 97 96.5 N.A. 35.7 81.1 N.A. 67.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 6.6 N.A. 86.6 86.6 N.A. 13.3 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 13.3 N.A. 86.6 86.6 N.A. 13.3 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 13 0 13 13 0 13 0 0 0 25 13 % A
% Cys: 50 0 0 0 0 0 0 0 0 0 13 0 13 0 0 % C
% Asp: 13 50 0 0 0 0 0 0 0 0 0 25 0 0 0 % D
% Glu: 13 0 0 0 63 0 0 0 0 0 13 0 13 0 0 % E
% Phe: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 13 50 0 0 38 0 50 50 50 13 0 13 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 0 0 0 0 0 0 13 0 13 0 25 0 % I
% Lys: 0 0 0 0 0 0 0 0 13 0 0 0 13 0 0 % K
% Leu: 0 0 0 0 0 63 0 13 0 0 0 0 0 0 13 % L
% Met: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 13 50 25 25 13 0 0 25 0 0 50 0 25 38 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % Q
% Arg: 0 0 13 0 0 0 0 0 13 13 0 0 0 0 0 % R
% Ser: 13 0 0 0 0 13 38 50 0 0 0 0 63 13 13 % S
% Thr: 13 0 0 0 0 13 13 13 0 0 0 0 0 0 13 % T
% Val: 0 13 0 13 0 0 0 13 0 13 13 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _