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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYBB3
All Species:
17.58
Human Site:
S125
Identified Species:
42.96
UniProt:
P26998
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26998
NP_004067.1
211
24230
S125
L
F
E
N
P
A
F
S
G
R
K
M
E
I
V
Chimpanzee
Pan troglodytes
XP_001171490
211
24168
S125
L
F
E
N
P
A
F
S
G
R
K
M
E
I
V
Rhesus Macaque
Macaca mulatta
A3RLD8
174
20712
R91
Q
T
G
S
H
R
L
R
L
Y
E
R
E
D
H
Dog
Lupus familis
XP_543459
248
27747
K156
L
F
E
G
A
N
F
K
G
K
T
M
E
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJU9
211
24273
S125
L
F
E
N
P
A
F
S
G
R
K
M
E
I
V
Rat
Rattus norvegicus
P02524
211
24316
S125
L
F
E
N
P
A
F
S
G
R
K
M
E
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512052
211
24214
G125
L
F
E
N
P
G
F
G
G
R
K
M
E
I
V
Chicken
Gallus gallus
P55165
211
24431
T125
L
F
E
N
A
G
Y
T
G
R
K
M
E
I
V
Frog
Xenopus laevis
NP_001087726
227
25921
N125
L
F
E
N
A
G
Y
N
G
R
K
M
E
I
V
Zebra Danio
Brachydanio rerio
Q6DGY7
183
21727
F100
E
Q
Y
R
M
E
L
F
E
G
C
N
Y
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
31.7
49.1
N.A.
92.4
91
N.A.
77.7
75.8
66.9
36.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
47.3
64.9
N.A.
95.7
95.2
N.A.
88.1
87.6
81.9
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
53.3
N.A.
100
100
N.A.
86.6
73.3
73.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
60
N.A.
100
100
N.A.
86.6
86.6
86.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
30
40
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
10
0
80
0
0
10
0
0
10
0
10
0
90
0
0
% E
% Phe:
0
80
0
0
0
0
60
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
30
0
10
80
10
0
0
0
0
10
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
70
0
0
0
0
% K
% Leu:
80
0
0
0
0
0
20
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
80
0
0
0
% M
% Asn:
0
0
0
70
0
10
0
10
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
10
0
10
0
10
0
70
0
10
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
40
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
10
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
20
0
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _