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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRYBB3 All Species: 13.94
Human Site: S51 Identified Species: 34.07
UniProt: P26998 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26998 NP_004067.1 211 24230 S51 E C P S L T D S L L E K V G S
Chimpanzee Pan troglodytes XP_001171490 211 24168 S51 E C P S L T D S L L E K V G S
Rhesus Macaque Macaca mulatta A3RLD8 174 20712 Y17 K A F Q G R S Y E S T T D C P
Dog Lupus familis XP_543459 248 27747 R82 E C L N L G D R G F D R V R S
Cat Felis silvestris
Mouse Mus musculus Q9JJU9 211 24273 S51 E C P N L T D S L L E K V G S
Rat Rattus norvegicus P02524 211 24316 S51 E C P N L T E S L L Q K V G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512052 211 24214 D51 E C P N L T E D R L E K V G S
Chicken Gallus gallus P55165 211 24431 K51 E L P N V V D K A L E K V G S
Frog Xenopus laevis NP_001087726 227 25921 K51 E C K N L S E K G L D K V G S
Zebra Danio Brachydanio rerio Q6DGY7 183 21727 D26 R C L E V Y G D C D N F Q D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 31.7 49.1 N.A. 92.4 91 N.A. 77.7 75.8 66.9 36.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 47.3 64.9 N.A. 95.7 95.2 N.A. 88.1 87.6 81.9 55.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 40 N.A. 93.3 80 N.A. 73.3 60 53.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 60 N.A. 100 100 N.A. 86.6 73.3 80 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % A
% Cys: 0 80 0 0 0 0 0 0 10 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 50 20 0 10 20 0 10 10 0 % D
% Glu: 80 0 0 10 0 0 30 0 10 0 50 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 10 0 10 0 0 0 % F
% Gly: 0 0 0 0 10 10 10 0 20 0 0 0 0 70 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 0 0 0 20 0 0 0 70 0 0 0 % K
% Leu: 0 10 20 0 70 0 0 0 40 70 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 60 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 10 0 10 0 0 % Q
% Arg: 10 0 0 0 0 10 0 10 10 0 0 10 0 10 10 % R
% Ser: 0 0 0 20 0 10 10 40 0 10 0 0 0 0 80 % S
% Thr: 0 0 0 0 0 50 0 0 0 0 10 10 0 0 0 % T
% Val: 0 0 0 0 20 10 0 0 0 0 0 0 80 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _