KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACVR2A
All Species:
36.67
Human Site:
Y168
Identified Species:
67.22
UniProt:
P27037
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27037
NP_001607.1
513
57848
Y168
Y
R
H
H
K
M
A
Y
P
P
V
L
V
P
T
Chimpanzee
Pan troglodytes
XP_001171684
516
58074
T170
R
K
P
P
Y
G
Q
T
F
L
S
L
A
L
P
Rhesus Macaque
Macaca mulatta
XP_001095641
521
58808
Y168
Y
R
H
H
K
M
A
Y
P
P
V
L
V
P
T
Dog
Lupus familis
XP_857260
513
57943
Y168
Y
R
H
H
K
M
A
Y
P
P
V
L
V
P
T
Cat
Felis silvestris
Mouse
Mus musculus
P27038
513
57871
Y168
Y
R
H
H
K
M
A
Y
P
P
V
L
V
P
T
Rat
Rattus norvegicus
P38444
513
57874
Y168
Y
R
H
H
M
M
A
Y
P
P
V
L
V
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518896
634
71047
Y317
Y
R
H
H
K
L
A
Y
P
P
S
G
Y
V
D
Chicken
Gallus gallus
Q90669
513
58073
Y168
Y
R
H
H
K
L
A
Y
P
P
V
L
V
P
T
Frog
Xenopus laevis
P27039
514
57885
Y169
Y
R
H
H
K
L
A
Y
P
P
V
L
V
P
T
Zebra Danio
Brachydanio rerio
NP_001103748
514
57908
Y169
Y
R
H
H
K
L
A
Y
P
P
V
L
V
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395928
531
60411
Y182
Y
R
R
R
K
S
G
Y
F
N
E
V
P
T
L
Nematode Worm
Caenorhab. elegans
P50488
744
84391
K261
W
K
F
Q
Q
N
K
K
E
E
I
K
K
Q
Q
Sea Urchin
Strong. purpuratus
XP_780388
541
60817
H170
M
C
R
R
H
R
Y
H
S
L
I
A
I
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67
98.4
98.8
N.A.
99.6
99
N.A.
53.7
92.5
87.9
78.7
N.A.
N.A.
53.4
25.2
51.3
Protein Similarity:
100
83.5
98.4
100
N.A.
100
99.6
N.A.
60.7
97.8
94.9
89.3
N.A.
N.A.
69.6
40.4
64.7
P-Site Identity:
100
6.6
100
100
N.A.
100
93.3
N.A.
60
93.3
93.3
93.3
N.A.
N.A.
26.6
0
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
93.3
N.A.
66.6
100
100
100
N.A.
N.A.
33.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
70
0
0
0
0
8
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
16
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% G
% His:
0
0
70
70
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
16
0
8
0
0
% I
% Lys:
0
16
0
0
70
0
8
8
0
0
0
8
8
0
0
% K
% Leu:
0
0
0
0
0
31
0
0
0
16
0
70
0
8
8
% L
% Met:
8
0
0
0
8
39
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
0
0
70
70
0
0
8
70
8
% P
% Gln:
0
0
0
8
8
0
8
0
0
0
0
0
0
8
8
% Q
% Arg:
8
77
16
16
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
0
8
0
16
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
70
% T
% Val:
0
0
0
0
0
0
0
0
0
0
62
8
62
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
77
0
0
0
8
0
8
77
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _