KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AK3L1
All Species:
33.64
Human Site:
S124
Identified Species:
67.27
UniProt:
P27144
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27144
NP_001005353.1
223
25268
S124
E
T
L
K
D
R
L
S
R
R
W
I
H
P
P
Chimpanzee
Pan troglodytes
XP_513462
353
38769
S254
E
T
L
K
D
R
L
S
R
R
W
I
H
P
P
Rhesus Macaque
Macaca mulatta
XP_001089239
223
25305
S124
E
T
L
K
D
R
L
S
R
R
W
I
H
P
P
Dog
Lupus familis
XP_546674
223
25374
S124
E
T
L
K
D
R
L
S
R
R
W
I
H
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUR9
223
25043
S124
E
T
L
K
D
R
L
S
R
R
W
I
H
P
S
Rat
Rattus norvegicus
Q9WUS0
223
25184
S124
E
T
L
K
D
R
L
S
R
R
W
I
H
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521544
260
29457
S161
E
T
L
K
D
R
L
S
R
R
W
I
H
P
S
Chicken
Gallus gallus
XP_422526
186
21368
G96
R
W
I
H
P
A
S
G
R
V
Y
N
M
E
F
Frog
Xenopus laevis
NP_001089446
221
24943
T125
Q
T
I
K
D
R
L
T
A
R
W
I
H
P
A
Zebra Danio
Brachydanio rerio
NP_998464
226
25423
R123
E
T
L
K
E
R
L
R
H
R
W
I
H
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788479
220
25045
E122
D
V
I
V
Q
R
L
E
W
R
W
I
H
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141169
227
25476
T126
E
V
I
K
L
R
L
T
A
R
W
I
H
P
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.6
99
95.5
N.A.
90.1
89.2
N.A.
61.5
67.2
58.2
64.1
N.A.
N.A.
N.A.
N.A.
54.7
Protein Similarity:
100
62.8
100
98.6
N.A.
94.1
95
N.A.
69.6
77.1
73.9
79.1
N.A.
N.A.
N.A.
N.A.
71.3
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
6.6
66.6
80
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
20
86.6
86.6
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
57.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
74.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
60
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
17
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
75
0
0
0
9
0
0
9
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% G
% His:
0
0
0
9
0
0
0
0
9
0
0
0
92
0
0
% H
% Ile:
0
0
34
0
0
0
0
0
0
0
0
92
0
0
0
% I
% Lys:
0
0
0
84
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
67
0
9
0
92
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
92
42
% P
% Gln:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
92
0
9
67
92
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
59
0
0
0
0
0
0
25
% S
% Thr:
0
75
0
0
0
0
0
17
0
0
0
0
0
0
0
% T
% Val:
0
17
0
9
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
9
0
92
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _