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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AK3L1 All Species: 22.73
Human Site: T215 Identified Species: 45.45
UniProt: P27144 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P27144 NP_001005353.1 223 25268 T215 T L F S N K I T P I Q S K E A
Chimpanzee Pan troglodytes XP_513462 353 38769 T345 T L F S N K I T P I Q S K E A
Rhesus Macaque Macaca mulatta XP_001089239 223 25305 T215 T L F S N K I T P I Q S K E A
Dog Lupus familis XP_546674 223 25374 T215 T L F S N K I T P I Q S K E A
Cat Felis silvestris
Mouse Mus musculus Q9WUR9 223 25043 T215 T L F S N K I T P I Q S K E A
Rat Rattus norvegicus Q9WUS0 223 25184 T215 T L F S N K I T P I Q S K E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521544 260 29457 P252 T L F S H K I P P T P S K E A
Chicken Gallus gallus XP_422526 186 21368 P179 L L S N K I P P L R S E E E H
Frog Xenopus laevis NP_001089446 221 24943 E209 K I W P H V Y E F L Q T K L S
Zebra Danio Brachydanio rerio NP_998464 226 25423 P214 T L L S T K I P A I Q S D A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788479 220 25045 Q213 D F L S G L L Q H P T K Q S E
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141169 227 25476 P217 S F L Q M K V P E T I Q K A S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.6 99 95.5 N.A. 90.1 89.2 N.A. 61.5 67.2 58.2 64.1 N.A. N.A. N.A. N.A. 54.7
Protein Similarity: 100 62.8 100 98.6 N.A. 94.1 95 N.A. 69.6 77.1 73.9 79.1 N.A. N.A. N.A. N.A. 71.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 13.3 13.3 53.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 26.6 53.3 53.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 57.2 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 74.4 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 0 0 0 0 17 59 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 9 0 0 9 9 67 9 % E
% Phe: 0 17 59 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 17 0 0 0 9 0 0 0 0 0 9 % H
% Ile: 0 9 0 0 0 9 67 0 0 59 9 0 0 0 0 % I
% Lys: 9 0 0 0 9 75 0 0 0 0 0 9 75 0 0 % K
% Leu: 9 75 25 0 0 9 9 0 9 9 0 0 0 9 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 50 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 9 34 59 9 9 0 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 9 0 0 67 9 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % R
% Ser: 9 0 9 75 0 0 0 0 0 0 9 67 0 9 17 % S
% Thr: 67 0 0 0 9 0 0 50 0 17 9 9 0 0 0 % T
% Val: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _