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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AK3L1
All Species:
35.76
Human Site:
Y174
Identified Species:
71.52
UniProt:
P27144
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27144
NP_001005353.1
223
25268
Y174
V
A
A
R
L
R
Q
Y
K
D
V
A
K
P
V
Chimpanzee
Pan troglodytes
XP_513462
353
38769
Y304
V
A
A
R
L
R
Q
Y
K
D
V
A
K
P
V
Rhesus Macaque
Macaca mulatta
XP_001089239
223
25305
Y174
V
A
A
R
L
R
Q
Y
K
D
V
A
K
P
V
Dog
Lupus familis
XP_546674
223
25374
Y174
V
A
A
R
L
R
Q
Y
K
D
V
A
K
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUR9
223
25043
Y174
V
A
A
R
L
R
R
Y
K
D
A
A
K
P
V
Rat
Rattus norvegicus
Q9WUS0
223
25184
Y174
L
A
A
R
L
R
R
Y
K
D
A
A
K
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521544
260
29457
Y211
V
A
A
R
L
R
Q
Y
K
G
A
A
K
P
V
Chicken
Gallus gallus
XP_422526
186
21368
K138
T
A
R
L
R
K
Y
K
D
A
A
K
P
V
I
Frog
Xenopus laevis
NP_001089446
221
24943
V168
E
D
D
K
P
E
T
V
T
K
R
L
N
G
Y
Zebra Danio
Brachydanio rerio
NP_998464
226
25423
Y173
L
V
A
R
L
R
H
Y
K
D
V
A
K
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788479
220
25045
Y172
V
R
A
R
L
D
L
Y
Q
Q
L
T
K
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141169
227
25476
Y176
V
I
K
R
L
K
A
Y
E
A
Q
T
E
P
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.6
99
95.5
N.A.
90.1
89.2
N.A.
61.5
67.2
58.2
64.1
N.A.
N.A.
N.A.
N.A.
54.7
Protein Similarity:
100
62.8
100
98.6
N.A.
94.1
95
N.A.
69.6
77.1
73.9
79.1
N.A.
N.A.
N.A.
N.A.
71.3
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
86.6
6.6
0
80
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
20
6.6
86.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
57.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
74.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
60
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
75
0
0
0
9
0
0
17
34
67
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
9
0
0
9
59
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
9
0
0
9
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
9
9
0
17
0
9
67
9
0
9
75
0
0
% K
% Leu:
17
0
0
9
84
0
9
0
0
0
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
9
84
0
% P
% Gln:
0
0
0
0
0
0
42
0
9
9
9
0
0
0
0
% Q
% Arg:
0
9
9
84
9
67
17
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
9
0
9
0
0
17
0
0
0
% T
% Val:
67
9
0
0
0
0
0
9
0
0
42
0
0
9
84
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
84
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _