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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AK3L1
All Species:
39.39
Human Site:
Y185
Identified Species:
78.79
UniProt:
P27144
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27144
NP_001005353.1
223
25268
Y185
A
K
P
V
I
E
L
Y
K
S
R
G
V
L
H
Chimpanzee
Pan troglodytes
XP_513462
353
38769
Y315
A
K
P
V
I
E
L
Y
K
S
R
G
V
L
H
Rhesus Macaque
Macaca mulatta
XP_001089239
223
25305
Y185
A
K
P
V
I
E
L
Y
K
S
R
G
V
L
H
Dog
Lupus familis
XP_546674
223
25374
Y185
A
K
P
V
I
E
L
Y
K
S
R
G
V
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUR9
223
25043
Y185
A
K
P
V
I
E
L
Y
K
S
R
G
V
L
H
Rat
Rattus norvegicus
Q9WUS0
223
25184
Y185
A
K
P
V
I
E
L
Y
K
S
R
G
V
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521544
260
29457
Y222
A
K
P
V
I
E
L
Y
K
S
R
G
I
L
H
Chicken
Gallus gallus
XP_422526
186
21368
K149
K
P
V
I
E
L
Y
K
S
R
G
I
L
H
S
Frog
Xenopus laevis
NP_001089446
221
24943
T179
L
N
G
Y
E
A
L
T
R
P
V
L
E
Y
Y
Zebra Danio
Brachydanio rerio
NP_998464
226
25423
Y184
A
K
P
V
I
D
F
Y
K
A
K
G
I
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788479
220
25045
Y183
T
K
P
V
L
E
F
Y
R
S
K
G
V
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141169
227
25476
Y187
T
E
P
V
L
Q
Y
Y
Q
K
K
G
V
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.6
99
95.5
N.A.
90.1
89.2
N.A.
61.5
67.2
58.2
64.1
N.A.
N.A.
N.A.
N.A.
54.7
Protein Similarity:
100
62.8
100
98.6
N.A.
94.1
95
N.A.
69.6
77.1
73.9
79.1
N.A.
N.A.
N.A.
N.A.
71.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
0
6.6
60
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
20
93.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
57.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
74.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
17
67
0
0
0
0
0
0
9
0
9
% E
% Phe:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
9
84
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
59
% H
% Ile:
0
0
0
9
67
0
0
0
0
0
0
9
17
0
0
% I
% Lys:
9
75
0
0
0
0
0
9
67
9
25
0
0
0
0
% K
% Leu:
9
0
0
0
17
9
67
0
0
0
0
9
9
84
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
84
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
17
9
59
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
9
67
0
0
0
0
9
% S
% Thr:
17
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
0
9
84
0
0
0
0
0
0
9
0
67
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
17
84
0
0
0
0
0
9
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _