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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PON1
All Species:
21.21
Human Site:
S296
Identified Species:
66.67
UniProt:
P27169
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27169
NP_000437.3
355
39749
S296
M
K
I
F
F
Y
D
S
E
N
P
P
A
S
E
Chimpanzee
Pan troglodytes
XP_519211
355
39709
S296
M
K
I
F
F
Y
D
S
E
N
P
P
A
S
E
Rhesus Macaque
Macaca mulatta
XP_001095992
355
39781
S296
M
K
V
F
F
Y
D
S
E
N
P
P
A
S
E
Dog
Lupus familis
XP_850219
355
40021
S296
I
R
I
F
F
Y
D
S
E
N
P
P
A
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P52430
355
39547
A296
M
R
I
F
F
Y
D
A
E
N
P
P
G
S
E
Rat
Rattus norvegicus
P55159
355
39478
S296
M
R
I
F
F
Y
D
S
E
N
P
P
G
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90952
354
39390
P295
M
K
L
F
Y
D
D
P
D
N
P
P
A
S
E
Frog
Xenopus laevis
NP_001084979
356
39849
S296
W
K
L
F
S
Y
N
S
D
D
L
P
G
S
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
95.7
87.6
N.A.
81.9
80
N.A.
N.A.
67.6
58.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.1
94.3
N.A.
92.3
90.1
N.A.
N.A.
80.8
75.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
80
86.6
N.A.
N.A.
66.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
13
0
0
0
0
63
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
88
0
25
13
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
100
% E
% Phe:
0
0
0
100
75
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
63
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
25
0
0
0
0
0
0
0
13
0
0
0
0
% L
% Met:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
0
0
88
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
0
88
100
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
38
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
13
0
0
75
0
0
0
0
0
100
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
88
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _