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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAQ
All Species:
13.64
Human Site:
T71
Identified Species:
25
UniProt:
P27348
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27348
NP_006817.1
245
27764
T71
S
I
E
Q
K
T
D
T
S
D
K
K
L
Q
L
Chimpanzee
Pan troglodytes
XP_525684
416
45456
T242
S
I
E
Q
K
T
D
T
S
D
K
K
L
Q
L
Rhesus Macaque
Macaca mulatta
XP_001097635
245
27803
T71
S
I
E
Q
K
T
D
T
S
D
K
K
L
Q
L
Dog
Lupus familis
XP_856222
224
25254
Q56
D
T
S
D
K
K
L
Q
L
I
K
D
Y
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV8
246
28068
R73
S
I
E
Q
K
T
E
R
N
E
K
K
Q
Q
M
Rat
Rattus norvegicus
P63102
245
27753
G71
S
I
E
Q
K
T
E
G
A
E
K
K
Q
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518806
277
31320
R104
S
I
E
Q
K
T
E
R
N
E
K
K
Q
Q
M
Chicken
Gallus gallus
Q5ZMD1
245
27764
T71
S
I
E
Q
K
T
D
T
S
D
K
K
M
Q
L
Frog
Xenopus laevis
Q8AVQ3
244
27740
G71
S
I
E
Q
K
T
E
G
N
D
K
R
Q
Q
M
Zebra Danio
Brachydanio rerio
Q5PRD0
244
27628
G71
S
I
E
Q
K
T
E
G
N
E
K
K
Q
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
A74
S
I
E
Q
K
T
E
A
S
A
R
K
Q
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
G73
S
I
E
Q
K
T
E
G
S
E
K
K
Q
Q
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
K76
Q
K
E
E
S
K
E
K
S
E
H
Q
V
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.8
99.1
91.4
N.A.
80.4
80
N.A.
72.9
98.7
77.5
78.3
N.A.
76.6
N.A.
75.4
N.A.
Protein Similarity:
100
58.8
99.1
91.4
N.A.
90.6
91
N.A.
80.5
100
90.6
89.8
N.A.
85.8
N.A.
83.8
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
60
60
N.A.
60
93.3
60
60
N.A.
66.6
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
86.6
86.6
N.A.
86.6
100
86.6
86.6
N.A.
80
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
31
0
0
39
0
8
0
0
0
% D
% Glu:
0
0
93
8
0
0
62
0
0
47
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
85
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
93
16
0
8
0
0
85
77
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
8
0
0
0
24
0
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
47
% M
% Asn:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
85
0
0
0
8
0
0
0
8
54
85
0
% Q
% Arg:
0
0
0
0
0
0
0
16
0
0
8
8
0
8
0
% R
% Ser:
85
0
8
0
8
0
0
0
54
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
85
0
31
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _