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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK3
All Species:
42.73
Human Site:
T111
Identified Species:
67.14
UniProt:
P27361
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27361
NP_001035145.1
379
43136
T111
R
D
I
L
R
A
S
T
L
E
A
M
R
D
V
Chimpanzee
Pan troglodytes
XP_510921
379
43006
T111
R
D
I
L
R
A
S
T
L
E
A
M
R
D
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854045
378
42847
T110
R
D
I
L
R
A
P
T
L
D
A
M
R
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q63844
380
43048
T112
R
D
I
L
R
A
P
T
L
E
A
M
R
D
V
Rat
Rattus norvegicus
P21708
380
43062
T112
R
D
I
L
R
A
P
T
L
E
A
M
R
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989481
368
41924
T102
N
D
I
I
R
A
P
T
I
E
Q
M
K
D
V
Frog
Xenopus laevis
P26696
361
41238
T97
N
D
I
I
R
A
P
T
I
E
Q
M
K
D
V
Zebra Danio
Brachydanio rerio
NP_958915
392
44081
H125
N
D
I
L
R
A
R
H
I
D
Y
M
R
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40417
426
49103
S157
R
D
I
L
R
V
D
S
I
D
Q
M
R
D
V
Honey Bee
Apis mellifera
XP_393029
371
42705
T96
R
D
I
L
R
A
P
T
I
E
Q
M
K
D
V
Nematode Worm
Caenorhab. elegans
P39745
444
50644
T165
Q
E
I
I
R
S
E
T
V
D
S
L
K
D
I
Sea Urchin
Strong. purpuratus
NP_999813
369
42176
T100
Q
D
I
I
K
A
D
T
I
E
A
M
R
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
R114
D
I
I
K
P
P
Q
R
E
N
F
N
D
V
Y
Baker's Yeast
Sacchar. cerevisiae
P16892
353
40754
S82
F
N
I
Q
R
P
D
S
F
E
N
F
N
E
V
Red Bread Mold
Neurospora crassa
Q96TL5
358
41225
F86
V
I
S
L
S
D
I
F
I
S
P
L
E
D
I
Conservation
Percent
Protein Identity:
100
95.7
N.A.
96.3
N.A.
96.8
97.1
N.A.
N.A.
83.1
82.3
82.4
N.A.
68.5
78.3
62.1
77.5
Protein Similarity:
100
96.8
N.A.
97.6
N.A.
97.1
97.3
N.A.
N.A.
88.3
87.5
87.2
N.A.
75.5
84.4
72.5
84.4
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
93.3
N.A.
N.A.
60
60
60
N.A.
60
73.3
26.6
66.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
80
73.3
N.A.
80
86.6
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.5
47.2
46.1
Protein Similarity:
N.A.
N.A.
N.A.
66.7
63.8
62.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
67
0
0
0
0
40
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
74
0
0
0
7
20
0
0
27
0
0
7
87
0
% D
% Glu:
0
7
0
0
0
0
7
0
7
60
0
0
7
7
0
% E
% Phe:
7
0
0
0
0
0
0
7
7
0
7
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
14
94
27
0
0
7
0
47
0
0
0
0
0
14
% I
% Lys:
0
0
0
7
7
0
0
0
0
0
0
0
27
0
0
% K
% Leu:
0
0
0
60
0
0
0
0
34
0
0
14
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
74
0
0
0
% M
% Asn:
20
7
0
0
0
0
0
0
0
7
7
7
7
0
0
% N
% Pro:
0
0
0
0
7
14
40
0
0
0
7
0
0
0
0
% P
% Gln:
14
0
0
7
0
0
7
0
0
0
27
0
0
0
0
% Q
% Arg:
47
0
0
0
80
0
7
7
0
0
0
0
54
0
0
% R
% Ser:
0
0
7
0
7
7
14
14
0
7
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
7
0
0
7
0
0
0
0
7
80
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _