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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK3
All Species:
29.39
Human Site:
T43
Identified Species:
46.19
UniProt:
P27361
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27361
NP_001035145.1
379
43136
T43
F
D
V
G
P
R
Y
T
Q
L
Q
Y
I
G
E
Chimpanzee
Pan troglodytes
XP_510921
379
43006
P43
F
D
A
G
P
D
S
P
F
V
R
P
Q
Q
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854045
378
42847
T42
F
D
V
G
P
R
Y
T
E
L
H
Y
I
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q63844
380
43048
T44
F
D
V
G
P
R
Y
T
Q
L
Q
Y
I
G
E
Rat
Rattus norvegicus
P21708
380
43062
T44
F
D
V
G
P
R
Y
T
Q
L
Q
Y
I
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989481
368
41924
T34
F
D
V
G
P
R
Y
T
N
L
S
Y
I
G
E
Frog
Xenopus laevis
P26696
361
41238
I29
F
D
V
G
P
R
Y
I
N
L
A
Y
I
G
E
Zebra Danio
Brachydanio rerio
NP_958915
392
44081
T57
F
D
V
G
P
R
Y
T
D
L
Q
Y
I
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40417
426
49103
I89
F
E
V
G
P
R
Y
I
K
L
A
Y
I
G
E
Honey Bee
Apis mellifera
XP_393029
371
42705
T28
F
E
V
G
P
R
Y
T
N
L
S
Y
M
G
E
Nematode Worm
Caenorhab. elegans
P39745
444
50644
V97
F
E
V
A
P
R
Y
V
N
L
S
Y
I
G
E
Sea Urchin
Strong. purpuratus
NP_999813
369
42176
V32
F
D
V
G
P
R
Y
V
T
L
N
Y
I
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
P44
E
V
S
R
K
Y
V
P
P
L
R
P
I
G
R
Baker's Yeast
Sacchar. cerevisiae
P16892
353
40754
Y24
S
L
L
G
E
G
A
Y
G
V
V
C
S
A
T
Red Bread Mold
Neurospora crassa
Q96TL5
358
41225
S21
F
E
I
T
S
R
Y
S
D
L
Q
P
V
G
M
Conservation
Percent
Protein Identity:
100
95.7
N.A.
96.3
N.A.
96.8
97.1
N.A.
N.A.
83.1
82.3
82.4
N.A.
68.5
78.3
62.1
77.5
Protein Similarity:
100
96.8
N.A.
97.6
N.A.
97.1
97.3
N.A.
N.A.
88.3
87.5
87.2
N.A.
75.5
84.4
72.5
84.4
P-Site Identity:
100
26.6
N.A.
86.6
N.A.
100
100
N.A.
N.A.
86.6
80
93.3
N.A.
73.3
73.3
66.6
80
P-Site Similarity:
100
46.6
N.A.
93.3
N.A.
100
100
N.A.
N.A.
86.6
80
93.3
N.A.
86.6
86.6
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.5
47.2
46.1
Protein Similarity:
N.A.
N.A.
N.A.
66.7
63.8
62.5
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
7
0
0
0
14
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
60
0
0
0
7
0
0
14
0
0
0
0
0
0
% D
% Glu:
7
27
0
0
7
0
0
0
7
0
0
0
0
0
74
% E
% Phe:
87
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
80
0
7
0
0
7
0
0
0
0
87
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
14
0
0
0
0
74
0
0
% I
% Lys:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% K
% Leu:
0
7
7
0
0
0
0
0
0
87
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
27
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
80
0
0
14
7
0
0
20
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
20
0
34
0
7
7
7
% Q
% Arg:
0
0
0
7
0
80
0
0
0
0
14
0
0
0
7
% R
% Ser:
7
0
7
0
7
0
7
7
0
0
20
0
7
0
0
% S
% Thr:
0
0
0
7
0
0
0
47
7
0
0
0
0
0
7
% T
% Val:
0
7
74
0
0
0
7
14
0
14
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
80
7
0
0
0
74
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _