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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARK3 All Species: 23.78
Human Site: T3 Identified Species: 47.55
UniProt: P27448 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P27448 NP_001122390.1 776 87005 T3 _ _ _ _ _ M S T R T P L P T V
Chimpanzee Pan troglodytes XP_510184 737 82858 T3 _ _ _ _ _ M S T R T P L P T V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_868647 777 86967 T3 _ _ _ _ _ M S T R T P L P T V
Cat Felis silvestris
Mouse Mus musculus Q03141 753 84371 T3 _ _ _ _ _ M S T R T P L P T V
Rat Rattus norvegicus Q8VHF0 797 88733 T3 _ _ _ _ _ M S T R T P L P T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508081 736 82480 F4 _ _ _ _ M S Q F L Q I T K H T
Chicken Gallus gallus Q9IA88 798 88848 L21 S A A Q P R P L R V G F Y D I
Frog Xenopus laevis NP_001084256 725 81522 T3 _ _ _ _ _ M S T R T P L P T V
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 S6 _ _ M A A V S S G A A A A A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 A117 T A S S G A P A A S S G G S S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163
Baker's Yeast Sacchar. cerevisiae P06782 633 72027
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 N.A. 96.4 N.A. 94 89.9 N.A. 90.5 31.4 85.6 26.5 N.A. N.A. N.A. 39.8 N.A.
Protein Similarity: 100 94.7 N.A. 97.4 N.A. 95 91.2 N.A. 92.9 50.7 89.5 42.6 N.A. N.A. N.A. 51 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 0 6.6 100 7.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 0 13.3 100 23 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. 44 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 9 9 9 0 9 9 9 9 9 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 9 0 9 9 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 0 0 0 0 0 0 0 9 9 0 0 50 0 0 0 % L
% Met: 0 0 9 0 9 50 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 17 0 0 0 50 0 50 0 0 % P
% Gln: 0 0 0 9 0 0 9 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 59 0 0 0 0 0 0 % R
% Ser: 9 0 9 9 0 9 59 9 0 9 9 0 0 9 9 % S
% Thr: 9 0 0 0 0 0 0 50 0 50 0 9 0 50 9 % T
% Val: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 67 67 59 59 50 0 0 0 0 0 0 0 0 0 0 % _