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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V0C
All Species:
54.55
Human Site:
T121
Identified Species:
75
UniProt:
P27449
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27449
NP_001685.1
155
15736
T121
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Chimpanzee
Pan troglodytes
XP_510748
156
15775
T122
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Rhesus Macaque
Macaca mulatta
XP_001085529
417
43146
T383
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Dog
Lupus familis
XP_537002
155
15683
T121
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91V37
205
21588
D166
G
S
G
A
A
L
A
D
A
Q
N
P
S
L
F
Rat
Rattus norvegicus
P63081
155
15789
T121
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232268
133
13418
V107
A
Q
Q
P
R
L
F
V
G
M
I
L
I
L
I
Frog
Xenopus laevis
NP_001082675
156
15788
T122
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Zebra Danio
Brachydanio rerio
NP_991117
153
15480
T119
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23380
159
16249
T125
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Honey Bee
Apis mellifera
NP_001011570
156
15953
T122
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Nematode Worm
Caenorhab. elegans
P34546
161
16391
T127
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Sea Urchin
Strong. purpuratus
XP_797801
155
15612
T121
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q41773
109
11025
F84
G
M
I
L
I
L
I
F
A
E
A
L
A
L
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59228
165
16624
N124
G
D
A
G
V
R
A
N
A
Q
Q
P
K
L
F
Baker's Yeast
Sacchar. cerevisiae
P25515
160
16332
S119
G
D
A
G
V
R
G
S
S
Q
Q
P
R
L
F
Red Bread Mold
Neurospora crassa
P31413
161
16311
T120
G
D
A
G
V
R
G
T
A
Q
Q
P
R
L
F
Conservation
Percent
Protein Identity:
100
98
35.2
96.7
N.A.
26.8
90.9
N.A.
N.A.
81.2
92.3
92.2
N.A.
80.5
80.7
66.4
82.5
Protein Similarity:
100
98.7
36.4
98.7
N.A.
43.9
96.1
N.A.
N.A.
83.8
95.5
94.8
N.A.
86.7
87.8
75.1
90.9
P-Site Identity:
100
100
100
100
N.A.
40
100
N.A.
N.A.
6.6
100
100
N.A.
100
100
100
100
P-Site Similarity:
100
100
100
100
N.A.
40
100
N.A.
N.A.
6.6
100
100
N.A.
100
100
100
100
Percent
Protein Identity:
N.A.
43.2
N.A.
60
68.7
70.1
Protein Similarity:
N.A.
50.9
N.A.
76.3
82.5
84.4
P-Site Identity:
N.A.
20
N.A.
80
86.6
100
P-Site Similarity:
N.A.
40
N.A.
86.6
100
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
83
6
6
0
12
0
89
0
6
0
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
83
0
0
0
0
0
6
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
6
6
0
0
0
0
0
0
89
% F
% Gly:
95
0
6
83
0
0
77
0
6
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
6
0
6
0
0
0
6
0
6
0
6
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% K
% Leu:
0
0
0
6
0
18
0
0
0
0
0
12
0
100
0
% L
% Met:
0
6
0
0
0
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
6
0
0
6
0
0
0
0
% N
% Pro:
0
0
0
6
0
0
0
0
0
0
0
89
0
0
0
% P
% Gln:
0
6
6
0
0
0
0
0
0
89
83
0
0
0
0
% Q
% Arg:
0
0
0
0
6
83
0
0
0
0
0
0
77
0
0
% R
% Ser:
0
6
0
0
0
0
0
6
6
0
0
0
6
0
0
% S
% Thr:
0
0
0
0
0
0
0
71
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
83
0
0
6
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _