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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPP4
All Species:
14.55
Human Site:
S460
Identified Species:
29.09
UniProt:
P27487
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27487
NP_001926.2
766
88279
S460
R
C
Q
Y
Y
S
V
S
F
S
K
E
A
K
Y
Chimpanzee
Pan troglodytes
Q5IS50
803
91393
S480
N
C
T
Y
F
S
A
S
F
S
H
S
M
D
F
Rhesus Macaque
Macaca mulatta
NP_001034279
766
87851
S460
R
C
Q
Y
Y
S
V
S
F
S
K
E
A
K
Y
Dog
Lupus familis
XP_535933
755
86978
S451
Q
Y
Y
S
V
L
F
S
K
D
A
K
Y
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
P28843
760
87418
S456
Q
Y
Y
A
V
S
F
S
K
E
A
K
Y
Y
Q
Rat
Rattus norvegicus
P14740
767
88070
S461
R
C
Q
Y
Y
S
V
S
L
S
K
E
A
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512879
748
86136
S444
Q
Y
Y
L
A
S
F
S
K
D
A
K
Y
Y
Q
Chicken
Gallus gallus
NP_001026426
759
86325
F455
C
Q
Y
Y
S
A
S
F
S
K
D
A
Q
Y
Y
Frog
Xenopus laevis
NP_001081519
748
85569
F444
C
Q
Q
Y
S
A
Y
F
S
K
N
S
K
Y
Y
Zebra Danio
Brachydanio rerio
NP_001154809
742
84650
K438
T
L
N
A
D
R
C
K
Y
N
S
A
T
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18253
829
94369
E512
Q
K
V
T
D
Q
F
E
D
C
K
T
L
G
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18962
818
93386
Q509
K
G
P
K
V
P
Y
Q
K
I
V
D
F
H
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.1
97.6
84.9
N.A.
84.4
84.8
N.A.
69.4
64.3
58.6
55.7
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
100
54.1
98.3
90.9
N.A.
92.3
92
N.A.
81.7
76.7
74
71.9
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Identity:
100
40
100
6.6
N.A.
13.3
93.3
N.A.
13.3
13.3
20
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
53.3
100
20
N.A.
26.6
93.3
N.A.
26.6
20
26.6
13.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
9
17
9
0
0
0
25
17
25
0
0
% A
% Cys:
17
34
0
0
0
0
9
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
17
0
0
0
9
17
9
9
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
9
0
25
0
0
0
% E
% Phe:
0
0
0
0
9
0
34
17
25
0
0
0
9
9
9
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
9
9
0
9
0
0
0
9
34
17
34
25
9
25
0
% K
% Leu:
0
9
0
9
0
9
0
0
9
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
9
9
0
0
0
0
% N
% Pro:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
34
17
34
0
0
9
0
9
0
0
0
0
9
0
25
% Q
% Arg:
25
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
17
50
9
59
17
34
9
17
0
0
25
% S
% Thr:
9
0
9
9
0
0
0
0
0
0
0
9
9
0
0
% T
% Val:
0
0
9
0
25
0
25
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
25
34
50
25
0
17
0
9
0
0
0
25
42
42
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _