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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPP4
All Species:
11.82
Human Site:
T481
Identified Species:
23.64
UniProt:
P27487
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27487
NP_001926.2
766
88279
T481
G
P
G
L
P
L
Y
T
L
H
S
S
V
N
D
Chimpanzee
Pan troglodytes
Q5IS50
803
91393
T501
G
P
G
V
P
M
V
T
V
H
N
T
T
D
K
Rhesus Macaque
Macaca mulatta
NP_001034279
766
87851
T481
G
P
G
L
P
L
Y
T
L
H
S
S
V
N
D
Dog
Lupus familis
XP_535933
755
86978
H472
G
L
P
L
Y
T
L
H
R
S
S
D
D
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P28843
760
87418
H477
G
L
P
L
Y
T
L
H
R
S
T
D
H
K
E
Rat
Rattus norvegicus
P14740
767
88070
T482
G
P
G
L
P
L
Y
T
L
H
R
S
T
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512879
748
86136
H465
G
L
P
L
Y
T
L
H
S
S
M
D
D
K
E
Chicken
Gallus gallus
NP_001026426
759
86325
L476
P
G
L
P
M
S
T
L
H
R
S
S
D
D
Q
Frog
Xenopus laevis
NP_001081519
748
85569
V465
P
G
L
P
I
Y
T
V
Y
N
S
S
N
D
N
Zebra Danio
Brachydanio rerio
NP_001154809
742
84650
G459
L
M
S
C
S
G
P
G
L
P
L
Y
T
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18253
829
94369
C533
G
Q
R
I
V
V
Q
C
E
K
P
F
D
N
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18962
818
93386
K530
D
K
G
N
V
L
G
K
S
L
Y
H
L
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.1
97.6
84.9
N.A.
84.4
84.8
N.A.
69.4
64.3
58.6
55.7
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
100
54.1
98.3
90.9
N.A.
92.3
92
N.A.
81.7
76.7
74
71.9
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Identity:
100
40
100
20
N.A.
13.3
73.3
N.A.
13.3
13.3
13.3
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
80
100
26.6
N.A.
26.6
80
N.A.
20
20
33.3
6.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
25
34
34
17
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
67
17
42
0
0
9
9
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
25
9
34
0
9
9
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
9
0
9
0
0
0
25
17
% K
% Leu:
9
25
17
50
0
34
25
9
34
9
9
0
9
9
0
% L
% Met:
0
9
0
0
9
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
9
9
0
9
25
9
% N
% Pro:
17
34
25
17
34
0
9
0
0
9
9
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
17
% Q
% Arg:
0
0
9
0
0
0
0
0
17
9
9
0
0
0
9
% R
% Ser:
0
0
9
0
9
9
0
0
17
25
42
42
0
0
0
% S
% Thr:
0
0
0
0
0
25
17
34
0
0
9
9
25
0
9
% T
% Val:
0
0
0
9
17
9
9
9
9
0
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
25
9
25
0
9
0
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _