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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPP4
All Species:
6.97
Human Site:
T52
Identified Species:
13.94
UniProt:
P27487
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27487
NP_001926.2
766
88279
T52
L
T
D
Y
L
K
N
T
Y
R
L
K
L
Y
S
Chimpanzee
Pan troglodytes
Q5IS50
803
91393
E72
Q
K
K
K
V
T
V
E
D
L
F
S
E
D
F
Rhesus Macaque
Macaca mulatta
NP_001034279
766
87851
T52
L
T
D
Y
L
K
N
T
Y
R
L
K
L
Y
S
Dog
Lupus familis
XP_535933
755
86978
F43
T
D
Y
L
K
N
T
F
R
V
K
F
Y
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P28843
760
87418
K48
Y
S
L
A
D
Y
L
K
S
T
F
R
V
K
S
Rat
Rattus norvegicus
P14740
767
88070
V53
Y
L
K
N
T
F
R
V
K
S
Y
S
L
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512879
748
86136
N36
S
L
N
D
Y
L
K
N
T
F
R
T
K
S
Y
Chicken
Gallus gallus
NP_001026426
759
86325
Y47
S
T
Y
T
L
E
N
Y
L
N
N
D
Y
V
Y
Frog
Xenopus laevis
NP_001081519
748
85569
D36
A
T
K
G
K
G
D
D
R
K
T
F
T
L
E
Zebra Danio
Brachydanio rerio
NP_001154809
742
84650
E30
P
T
A
I
L
L
K
E
D
K
S
E
P
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18253
829
94369
Y104
G
K
Q
F
L
V
D
Y
Y
D
Y
I
W
L
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18962
818
93386
D101
D
N
K
I
E
S
N
D
L
G
L
Y
V
T
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.1
97.6
84.9
N.A.
84.4
84.8
N.A.
69.4
64.3
58.6
55.7
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
100
54.1
98.3
90.9
N.A.
92.3
92
N.A.
81.7
76.7
74
71.9
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Identity:
100
0
100
0
N.A.
6.6
6.6
N.A.
0
20
6.6
13.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
6.6
100
0
N.A.
26.6
6.6
N.A.
6.6
26.6
20
26.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
17
9
9
0
17
17
17
9
0
9
0
9
0
% D
% Glu:
0
0
0
0
9
9
0
17
0
0
0
9
9
0
9
% E
% Phe:
0
0
0
9
0
9
0
9
0
9
17
17
0
0
17
% F
% Gly:
9
0
0
9
0
9
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
17
34
9
17
17
17
9
9
17
9
17
9
9
9
% K
% Leu:
17
17
9
9
42
17
9
0
17
9
25
0
25
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
9
0
9
34
9
0
9
9
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% P
% Gln:
9
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
9
0
17
17
9
9
0
9
0
% R
% Ser:
17
9
0
0
0
9
0
0
9
9
9
17
0
17
25
% S
% Thr:
9
42
0
9
9
9
9
17
9
9
9
9
9
9
0
% T
% Val:
0
0
0
0
9
9
9
9
0
9
0
0
17
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% W
% Tyr:
17
0
17
17
9
9
0
17
25
0
17
9
17
17
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _