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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LASS1 All Species: 12.73
Human Site: S330 Identified Species: 20
UniProt: P27544 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P27544 NP_067090.1 350 39536 S330 Y D T A E A Q S L K P S K A E
Chimpanzee Pan troglodytes XP_524160 413 46292 S380 Y D T A E A Q S L K P S K A E
Rhesus Macaque Macaca mulatta XP_001115596 252 29440 P241 K P S K A E K P L R N G L V K
Dog Lupus familis XP_852219 170 19061 A159 H R L H A L A A D L G C L S F
Cat Felis silvestris
Mouse Mus musculus P27545 350 40082 T330 Y D T L E A Q T A K P C K A E
Rat Rattus norvegicus NP_001037695 350 39960 T330 Y D S L E A Q T A K P C R A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509533 301 35212 R290 S P P A L S L R K E G S L K T
Chicken Gallus gallus XP_418236 354 41217 K321 Y D V E D S K K T T A A K K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696339 371 43596 E334 Y D E D D L K E R K D S S D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493403 360 42724 S338 E W D T T A V S G L N Q Q K L
Sea Urchin Strong. purpuratus XP_796958 456 53475 D409 R E E N E H I D A D G N V K E
Poplar Tree Populus trichocarpa XP_002311424 308 36356 R297 G H L S D D V R S D S E G E D
Maize Zea mays NP_001149162 313 36527 V301 K G H V G D D V R S D S E G E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDF2 310 36479 R299 G K L S E D V R S D S E S D D
Baker's Yeast Sacchar. cerevisiae P28496 418 48974 E403 E S D E E S D E S S T T P T D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.8 70.8 35.4 N.A. 80.8 80.5 N.A. 64 70.9 N.A. 52.5 N.A. N.A. N.A. 32.2 30.2
Protein Similarity: 100 82.5 70.8 40.5 N.A. 87.4 88 N.A. 71.7 79.6 N.A. 68.1 N.A. N.A. N.A. 48.3 45.3
P-Site Identity: 100 100 6.6 0 N.A. 73.3 60 N.A. 13.3 20 N.A. 33.3 N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: 100 100 33.3 20 N.A. 80 80 N.A. 26.6 53.3 N.A. 46.6 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: 24.5 27.1 N.A. 22.8 20.3 N.A.
Protein Similarity: 40.8 41.4 N.A. 40 33.4 N.A.
P-Site Identity: 0 13.3 N.A. 6.6 6.6 N.A.
P-Site Similarity: 20 20 N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 14 34 7 7 20 0 7 7 0 27 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % C
% Asp: 0 40 14 7 20 20 14 7 7 20 14 0 0 14 20 % D
% Glu: 14 7 14 14 47 7 0 14 0 7 0 14 7 7 47 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 14 7 0 0 7 0 0 0 7 0 20 7 7 7 0 % G
% His: 7 7 7 7 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 14 7 0 7 0 0 20 7 7 34 0 0 27 27 14 % K
% Leu: 0 0 20 14 7 14 7 0 20 14 0 0 20 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 0 14 7 0 0 0 % N
% Pro: 0 14 7 0 0 0 0 7 0 0 27 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 27 0 0 0 0 7 7 0 0 % Q
% Arg: 7 7 0 0 0 0 0 20 14 7 0 0 7 0 0 % R
% Ser: 7 7 14 14 0 20 0 20 20 14 14 34 14 7 0 % S
% Thr: 0 0 20 7 7 0 0 14 7 7 7 7 0 7 7 % T
% Val: 0 0 7 7 0 0 20 7 0 0 0 0 7 7 0 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _