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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASS1
All Species:
22.12
Human Site:
T274
Identified Species:
34.76
UniProt:
P27544
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27544
NP_067090.1
350
39536
T274
T
S
H
C
S
L
R
T
V
P
D
I
P
F
Y
Chimpanzee
Pan troglodytes
XP_524160
413
46292
T324
T
S
H
C
S
L
R
T
V
P
D
I
P
F
Y
Rhesus Macaque
Macaca mulatta
XP_001115596
252
29440
F185
P
D
I
P
F
Y
F
F
F
N
A
L
L
L
L
Dog
Lupus familis
XP_852219
170
19061
I103
G
K
R
L
V
S
A
I
G
G
K
F
G
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P27545
350
40082
S274
T
C
H
C
S
L
Q
S
V
P
D
I
P
Y
Y
Rat
Rattus norvegicus
NP_001037695
350
39960
S274
T
W
H
C
S
L
Q
S
V
P
D
I
P
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509533
301
35212
P234
L
R
S
V
P
N
I
P
F
Y
F
F
F
N
T
Chicken
Gallus gallus
XP_418236
354
41217
S265
T
C
Y
S
S
L
Q
S
V
P
N
I
P
F
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696339
371
43596
S278
S
C
I
T
S
I
Q
S
V
P
N
I
P
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493403
360
42724
Y282
A
T
I
Y
G
A
V
Y
L
G
P
Q
D
A
P
Sea Urchin
Strong. purpuratus
XP_796958
456
53475
T353
V
L
P
S
T
A
K
T
Y
Y
K
G
H
L
P
Poplar Tree
Populus trichocarpa
XP_002311424
308
36356
L241
W
S
T
S
Y
E
V
L
L
I
L
D
K
E
K
Maize
Zea mays
NP_001149162
313
36527
V245
L
R
S
T
S
Y
E
V
L
L
T
L
D
K
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDF2
310
36479
I243
L
W
S
T
S
Y
Q
I
I
M
T
V
D
K
E
Baker's Yeast
Sacchar. cerevisiae
P28496
418
48974
Q347
V
L
N
F
A
T
Q
Q
Y
K
C
W
I
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.8
70.8
35.4
N.A.
80.8
80.5
N.A.
64
70.9
N.A.
52.5
N.A.
N.A.
N.A.
32.2
30.2
Protein Similarity:
100
82.5
70.8
40.5
N.A.
87.4
88
N.A.
71.7
79.6
N.A.
68.1
N.A.
N.A.
N.A.
48.3
45.3
P-Site Identity:
100
100
0
0
N.A.
73.3
73.3
N.A.
0
60
N.A.
46.6
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
6.6
0
N.A.
93.3
93.3
N.A.
0
86.6
N.A.
80
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
24.5
27.1
N.A.
22.8
20.3
N.A.
Protein Similarity:
40.8
41.4
N.A.
40
33.4
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
13.3
20
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
14
7
0
0
0
7
0
0
7
0
% A
% Cys:
0
20
0
27
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
0
27
7
20
0
0
% D
% Glu:
0
0
0
0
0
7
7
0
0
0
0
0
0
7
14
% E
% Phe:
0
0
0
7
7
0
7
7
14
0
7
14
7
27
0
% F
% Gly:
7
0
0
0
7
0
0
0
7
14
0
7
7
0
0
% G
% His:
0
0
27
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
20
0
0
7
7
14
7
7
0
40
7
0
0
% I
% Lys:
0
7
0
0
0
0
7
0
0
7
14
0
7
14
7
% K
% Leu:
20
14
0
7
0
34
0
7
20
7
7
14
7
14
20
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
0
0
7
14
0
0
7
0
% N
% Pro:
7
0
7
7
7
0
0
7
0
40
7
0
40
0
14
% P
% Gln:
0
0
0
0
0
0
40
7
0
0
0
7
0
0
0
% Q
% Arg:
0
14
7
0
0
0
14
0
0
0
0
0
0
0
0
% R
% Ser:
7
20
20
20
54
7
0
27
0
0
0
0
0
7
0
% S
% Thr:
34
7
7
20
7
7
0
20
0
0
14
0
0
0
7
% T
% Val:
14
0
0
7
7
0
14
7
40
0
0
7
0
7
0
% V
% Trp:
7
14
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
7
7
7
20
0
7
14
14
0
0
0
14
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _