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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASS1
All Species:
13.94
Human Site:
T325
Identified Species:
21.9
UniProt:
P27544
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27544
NP_067090.1
350
39536
T325
K
D
L
R
E
Y
D
T
A
E
A
Q
S
L
K
Chimpanzee
Pan troglodytes
XP_524160
413
46292
T375
K
D
L
R
E
Y
D
T
A
E
A
Q
S
L
K
Rhesus Macaque
Macaca mulatta
XP_001115596
252
29440
S236
E
A
Q
S
L
K
P
S
K
A
E
K
P
L
R
Dog
Lupus familis
XP_852219
170
19061
L154
R
G
G
S
H
H
R
L
H
A
L
A
A
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P27545
350
40082
T325
E
D
L
R
E
Y
D
T
L
E
A
Q
T
A
K
Rat
Rattus norvegicus
NP_001037695
350
39960
S325
E
D
L
R
E
Y
D
S
L
E
A
Q
T
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509533
301
35212
P285
Y
D
V
D
E
S
P
P
A
L
S
L
R
K
E
Chicken
Gallus gallus
XP_418236
354
41217
V316
N
D
V
R
E
Y
D
V
E
D
S
K
K
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696339
371
43596
E329
N
D
V
R
E
Y
D
E
D
D
L
K
E
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493403
360
42724
D333
P
E
D
N
R
E
W
D
T
T
A
V
S
G
L
Sea Urchin
Strong. purpuratus
XP_796958
456
53475
E404
E
F
E
D
I
R
E
E
N
E
H
I
D
A
D
Poplar Tree
Populus trichocarpa
XP_002311424
308
36356
L292
Q
I
Q
A
R
G
H
L
S
D
D
V
R
S
D
Maize
Zea mays
NP_001149162
313
36527
H296
K
Q
I
Q
S
K
G
H
V
G
D
D
V
R
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDF2
310
36479
L294
Q
V
Q
D
R
G
K
L
S
E
D
V
R
S
D
Baker's Yeast
Sacchar. cerevisiae
P28496
418
48974
D398
D
R
S
D
S
E
S
D
E
E
S
D
E
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.8
70.8
35.4
N.A.
80.8
80.5
N.A.
64
70.9
N.A.
52.5
N.A.
N.A.
N.A.
32.2
30.2
Protein Similarity:
100
82.5
70.8
40.5
N.A.
87.4
88
N.A.
71.7
79.6
N.A.
68.1
N.A.
N.A.
N.A.
48.3
45.3
P-Site Identity:
100
100
6.6
0
N.A.
73.3
66.6
N.A.
20
33.3
N.A.
40
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
33.3
20
N.A.
86.6
86.6
N.A.
40
60
N.A.
60
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
24.5
27.1
N.A.
22.8
20.3
N.A.
Protein Similarity:
40.8
41.4
N.A.
40
33.4
N.A.
P-Site Identity:
0
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
20
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
20
14
34
7
7
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
47
7
27
0
0
40
14
7
20
20
14
7
7
20
% D
% Glu:
27
7
7
0
47
14
7
14
14
47
7
0
14
0
7
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
14
7
0
0
7
0
0
0
7
0
% G
% His:
0
0
0
0
7
7
7
7
7
0
7
0
0
0
0
% H
% Ile:
0
7
7
0
7
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
20
0
0
0
0
14
7
0
7
0
0
20
7
7
34
% K
% Leu:
0
0
27
0
7
0
0
20
14
7
14
7
0
20
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
14
7
0
0
0
0
7
0
0
% P
% Gln:
14
7
20
7
0
0
0
0
0
0
0
27
0
0
0
% Q
% Arg:
7
7
0
40
20
7
7
0
0
0
0
0
20
14
7
% R
% Ser:
0
0
7
14
14
7
7
14
14
0
20
0
20
20
14
% S
% Thr:
0
0
0
0
0
0
0
20
7
7
0
0
14
7
7
% T
% Val:
0
7
20
0
0
0
0
7
7
0
0
20
7
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _