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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASS1
All Species:
22.12
Human Site:
Y118
Identified Species:
34.76
UniProt:
P27544
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27544
NP_067090.1
350
39536
Y118
G
S
W
S
Y
S
A
Y
L
L
F
G
T
D
Y
Chimpanzee
Pan troglodytes
XP_524160
413
46292
Y168
G
S
W
S
Y
S
A
Y
L
L
F
G
T
D
Y
Rhesus Macaque
Macaca mulatta
XP_001115596
252
29440
F29
L
F
G
T
D
Y
P
F
F
H
D
P
P
S
V
Dog
Lupus familis
XP_852219
170
19061
Cat
Felis silvestris
Mouse
Mus musculus
P27545
350
40082
Y118
A
C
W
S
Y
C
A
Y
L
L
L
G
T
S
Y
Rat
Rattus norvegicus
NP_001037695
350
39960
Y118
A
C
W
S
Y
C
A
Y
L
L
L
G
T
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509533
301
35212
T78
S
A
Y
L
L
F
G
T
D
Y
P
F
F
H
D
Chicken
Gallus gallus
XP_418236
354
41217
Y109
I
S
W
S
Y
G
F
Y
L
L
F
F
T
D
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696339
371
43596
Y122
M
S
W
S
Y
S
T
Y
L
L
F
F
T
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493403
360
42724
M126
I
F
A
F
Y
F
H
M
C
V
D
S
H
D
I
Sea Urchin
Strong. purpuratus
XP_796958
456
53475
Y110
T
S
W
S
C
V
A
Y
V
L
L
W
N
H
A
Poplar Tree
Populus trichocarpa
XP_002311424
308
36356
F85
S
A
W
K
C
I
Y
F
L
S
S
E
I
L
V
Maize
Zea mays
NP_001149162
313
36527
Y89
E
S
A
W
K
F
V
Y
F
L
S
G
E
L
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDF2
310
36479
Y87
E
S
A
W
K
C
I
Y
Y
L
S
A
E
L
L
Baker's Yeast
Sacchar. cerevisiae
P28496
418
48974
I191
G
V
S
G
P
F
G
I
Y
C
M
Y
H
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.8
70.8
35.4
N.A.
80.8
80.5
N.A.
64
70.9
N.A.
52.5
N.A.
N.A.
N.A.
32.2
30.2
Protein Similarity:
100
82.5
70.8
40.5
N.A.
87.4
88
N.A.
71.7
79.6
N.A.
68.1
N.A.
N.A.
N.A.
48.3
45.3
P-Site Identity:
100
100
0
0
N.A.
66.6
66.6
N.A.
0
73.3
N.A.
73.3
N.A.
N.A.
N.A.
13.3
40
P-Site Similarity:
100
100
13.3
0
N.A.
66.6
66.6
N.A.
13.3
73.3
N.A.
73.3
N.A.
N.A.
N.A.
20
46.6
Percent
Protein Identity:
24.5
27.1
N.A.
22.8
20.3
N.A.
Protein Similarity:
40.8
41.4
N.A.
40
33.4
N.A.
P-Site Identity:
13.3
26.6
N.A.
20
6.6
N.A.
P-Site Similarity:
26.6
26.6
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
20
0
0
0
34
0
0
0
0
7
0
0
7
% A
% Cys:
0
14
0
0
14
20
0
0
7
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
7
0
14
0
0
27
14
% D
% Glu:
14
0
0
0
0
0
0
0
0
0
0
7
14
0
0
% E
% Phe:
0
14
0
7
0
27
7
14
14
0
27
20
7
0
0
% F
% Gly:
20
0
7
7
0
7
14
0
0
0
0
34
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
7
0
0
14
14
0
% H
% Ile:
14
0
0
0
0
7
7
7
0
0
0
0
7
0
7
% I
% Lys:
0
0
0
7
14
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
0
7
7
0
0
0
47
60
20
0
0
20
14
% L
% Met:
7
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
7
0
7
0
0
0
7
7
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
14
47
7
47
0
20
0
0
0
7
20
7
0
34
0
% S
% Thr:
7
0
0
7
0
0
7
7
0
0
0
0
40
0
0
% T
% Val:
0
7
0
0
0
7
7
0
7
7
0
0
0
0
14
% V
% Trp:
0
0
54
14
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
7
0
47
7
7
60
14
7
0
7
0
0
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _