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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASS1
All Species:
22.12
Human Site:
Y168
Identified Species:
34.76
UniProt:
P27544
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27544
NP_067090.1
350
39536
Y168
H
S
I
Y
A
T
L
Y
M
D
T
W
R
K
D
Chimpanzee
Pan troglodytes
XP_524160
413
46292
Y218
H
S
I
Y
A
T
L
Y
M
D
T
W
R
K
D
Rhesus Macaque
Macaca mulatta
XP_001115596
252
29440
V79
D
T
W
R
K
D
S
V
V
M
L
L
H
H
V
Dog
Lupus familis
XP_852219
170
19061
Cat
Felis silvestris
Mouse
Mus musculus
P27545
350
40082
Y168
H
S
I
Y
A
T
V
Y
M
D
S
W
R
K
D
Rat
Rattus norvegicus
NP_001037695
350
39960
Y168
H
S
V
Y
A
T
V
Y
M
D
S
W
R
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509533
301
35212
R128
T
L
Y
M
D
S
W
R
K
D
S
V
V
M
L
Chicken
Gallus gallus
XP_418236
354
41217
Y159
H
S
I
Y
A
T
A
Y
M
D
T
W
R
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696339
371
43596
Y172
H
S
I
Y
A
T
V
Y
M
D
E
W
R
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493403
360
42724
F176
H
S
I
Y
A
T
L
F
M
D
L
W
R
K
D
Sea Urchin
Strong. purpuratus
XP_796958
456
53475
V247
H
G
L
V
T
V
L
V
L
D
V
W
R
S
D
Poplar Tree
Populus trichocarpa
XP_002311424
308
36356
G135
A
V
Y
M
Y
A
A
G
F
Y
T
Y
S
I
F
Maize
Zea mays
NP_001149162
313
36527
A139
K
A
V
Y
M
Y
A
A
G
F
Y
T
Y
S
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDF2
310
36479
A137
K
F
L
Y
M
F
A
A
G
F
Y
T
Y
S
I
Baker's Yeast
Sacchar. cerevisiae
P28496
418
48974
Q241
Q
A
C
I
L
V
L
Q
L
E
K
P
R
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.8
70.8
35.4
N.A.
80.8
80.5
N.A.
64
70.9
N.A.
52.5
N.A.
N.A.
N.A.
32.2
30.2
Protein Similarity:
100
82.5
70.8
40.5
N.A.
87.4
88
N.A.
71.7
79.6
N.A.
68.1
N.A.
N.A.
N.A.
48.3
45.3
P-Site Identity:
100
100
0
0
N.A.
86.6
80
N.A.
6.6
93.3
N.A.
86.6
N.A.
N.A.
N.A.
86.6
40
P-Site Similarity:
100
100
13.3
0
N.A.
100
100
N.A.
20
93.3
N.A.
93.3
N.A.
N.A.
N.A.
93.3
53.3
Percent
Protein Identity:
24.5
27.1
N.A.
22.8
20.3
N.A.
Protein Similarity:
40.8
41.4
N.A.
40
33.4
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
26.6
N.A.
P-Site Similarity:
13.3
20
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
0
0
47
7
27
14
0
0
0
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
7
0
0
0
60
0
0
0
0
60
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% E
% Phe:
0
7
0
0
0
7
0
7
7
14
0
0
0
0
7
% F
% Gly:
0
7
0
0
0
0
0
7
14
0
0
0
0
0
0
% G
% His:
54
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
0
0
40
7
0
0
0
0
0
0
0
0
0
7
14
% I
% Lys:
14
0
0
0
7
0
0
0
7
0
7
0
0
54
0
% K
% Leu:
0
7
14
0
7
0
34
0
14
0
14
7
0
0
7
% L
% Met:
0
0
0
14
14
0
0
0
47
7
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
7
0
0
0
0
60
0
0
% R
% Ser:
0
47
0
0
0
7
7
0
0
0
20
0
7
20
0
% S
% Thr:
7
7
0
0
7
47
0
0
0
0
27
14
0
0
0
% T
% Val:
0
7
14
7
0
14
20
14
7
0
7
7
7
0
7
% V
% Trp:
0
0
7
0
0
0
7
0
0
0
0
54
0
0
0
% W
% Tyr:
0
0
14
60
7
7
0
40
0
7
14
7
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _