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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASS1
All Species:
29.39
Human Site:
Y224
Identified Species:
46.19
UniProt:
P27544
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27544
NP_067090.1
350
39536
Y224
E
F
T
K
L
N
I
Y
F
K
S
R
G
G
S
Chimpanzee
Pan troglodytes
XP_524160
413
46292
Y274
E
F
T
K
L
N
I
Y
F
K
S
R
G
G
S
Rhesus Macaque
Macaca mulatta
XP_001115596
252
29440
H135
K
S
R
G
G
S
Y
H
R
L
H
A
L
A
A
Dog
Lupus familis
XP_852219
170
19061
L53
P
E
S
A
W
K
F
L
F
Y
L
G
A
W
S
Cat
Felis silvestris
Mouse
Mus musculus
P27545
350
40082
Y224
E
F
T
K
L
N
I
Y
F
K
A
R
G
G
A
Rat
Rattus norvegicus
NP_001037695
350
39960
Y224
E
F
T
K
L
N
I
Y
F
K
A
R
G
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509533
301
35212
G184
N
V
Y
F
K
L
R
G
G
V
Y
H
R
L
N
Chicken
Gallus gallus
XP_418236
354
41217
Y215
E
F
T
K
L
N
V
Y
F
K
H
R
G
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696339
371
43596
Y228
E
F
T
K
I
N
V
Y
F
K
T
R
G
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493403
360
42724
Y232
E
I
T
K
L
S
F
Y
L
K
K
R
T
N
R
Sea Urchin
Strong. purpuratus
XP_796958
456
53475
Y303
E
F
S
K
C
H
I
Y
L
K
D
R
G
N
K
Poplar Tree
Populus trichocarpa
XP_002311424
308
36356
D191
L
A
I
H
D
A
S
D
V
F
L
E
V
G
K
Maize
Zea mays
NP_001149162
313
36527
S195
V
L
A
L
H
D
A
S
D
I
F
L
E
I
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDF2
310
36479
S193
I
L
A
L
H
D
A
S
D
V
F
L
E
I
G
Baker's Yeast
Sacchar. cerevisiae
P28496
418
48974
Y297
S
F
S
K
T
L
N
Y
L
D
S
G
L
A
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.8
70.8
35.4
N.A.
80.8
80.5
N.A.
64
70.9
N.A.
52.5
N.A.
N.A.
N.A.
32.2
30.2
Protein Similarity:
100
82.5
70.8
40.5
N.A.
87.4
88
N.A.
71.7
79.6
N.A.
68.1
N.A.
N.A.
N.A.
48.3
45.3
P-Site Identity:
100
100
0
13.3
N.A.
86.6
86.6
N.A.
0
80
N.A.
73.3
N.A.
N.A.
N.A.
46.6
53.3
P-Site Similarity:
100
100
26.6
20
N.A.
100
100
N.A.
6.6
86.6
N.A.
93.3
N.A.
N.A.
N.A.
53.3
66.6
Percent
Protein Identity:
24.5
27.1
N.A.
22.8
20.3
N.A.
Protein Similarity:
40.8
41.4
N.A.
40
33.4
N.A.
P-Site Identity:
6.6
0
N.A.
0
26.6
N.A.
P-Site Similarity:
6.6
6.6
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
7
0
7
14
0
0
0
14
7
7
14
20
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
14
0
7
14
7
7
0
0
0
0
% D
% Glu:
54
7
0
0
0
0
0
0
0
0
0
7
14
0
0
% E
% Phe:
0
54
0
7
0
0
14
0
47
7
14
0
0
0
7
% F
% Gly:
0
0
0
7
7
0
0
7
7
0
0
14
47
47
14
% G
% His:
0
0
0
7
14
7
0
7
0
0
14
7
0
0
0
% H
% Ile:
7
7
7
0
7
0
34
0
0
7
0
0
0
14
0
% I
% Lys:
7
0
0
60
7
7
0
0
0
54
7
0
0
0
20
% K
% Leu:
7
14
0
14
40
14
0
7
20
7
14
14
14
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
40
7
0
0
0
0
0
0
14
7
% N
% Pro:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
7
0
7
0
0
54
7
0
7
% R
% Ser:
7
7
20
0
0
14
7
14
0
0
20
0
0
0
20
% S
% Thr:
0
0
47
0
7
0
0
0
0
0
7
0
7
0
0
% T
% Val:
7
7
0
0
0
0
14
0
7
14
0
0
7
0
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
7
0
0
0
7
60
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _