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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPA1 All Species: 22.73
Human Site: S223 Identified Species: 41.67
UniProt: P27694 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P27694 NP_002936.1 616 68138 S223 R G E G K L F S L E L V D E S
Chimpanzee Pan troglodytes XP_511254 670 73536 S277 R G E G K L F S L E L V D E S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548316 616 68389 S223 R G E G K L F S I E L V D E S
Cat Felis silvestris
Mouse Mus musculus Q8VEE4 623 69019 S232 R G E G K L F S L E L V D E S
Rat Rattus norvegicus NP_001041308 680 75055 N261 K Q F S A V K N D Y E M T F N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507100 619 68389 S223 R G E G K L F S I E L V D E S
Chicken Gallus gallus Q5ZJJ2 614 67982 S220 R G E G K L F S I E L V D E S
Frog Xenopus laevis Q01588 609 67067 V218 K L F S I E M V D E S G E I R
Zebra Danio Brachydanio rerio Q6NY74 601 66612 A222 D E S G E I R A T G F N N E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24492 603 66606 A219 S G E I R A T A F K E Q C D K
Honey Bee Apis mellifera XP_001121722 597 67108 N218 I R C T A F R N E C D K F Y D
Nematode Worm Caenorhab. elegans Q19537 655 73183 E262 N T K V F N F E I T D S N G D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22336 621 70329 N223 R G D G K L F N V N F L D T S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.4 N.A. 88.4 N.A. 84.5 78.3 N.A. 82.3 74.6 72.8 63.9 N.A. 43.1 42.3 27 N.A.
Protein Similarity: 100 91.6 N.A. 94.3 N.A. 91.3 83.3 N.A. 91.5 86.1 87.5 80.6 N.A. 62.5 64.4 47.9 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 0 N.A. 93.3 93.3 6.6 13.3 N.A. 13.3 0 6.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 33.3 N.A. 100 100 20 40 N.A. 40 6.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 16 8 0 16 0 0 0 0 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 8 0 0 8 0 0 % C
% Asp: 8 0 8 0 0 0 0 0 16 0 16 0 54 8 16 % D
% Glu: 0 8 54 0 8 8 0 8 8 54 16 0 8 54 0 % E
% Phe: 0 0 16 0 8 8 62 0 8 0 16 0 8 8 0 % F
% Gly: 0 62 0 62 0 0 0 0 0 8 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 8 8 8 0 0 31 0 0 0 0 8 0 % I
% Lys: 16 0 8 0 54 0 8 0 0 8 0 8 0 0 8 % K
% Leu: 0 8 0 0 0 54 0 0 24 0 47 8 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % M
% Asn: 8 0 0 0 0 8 0 24 0 8 0 8 16 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 54 8 0 0 8 0 16 0 0 0 0 0 0 0 8 % R
% Ser: 8 0 8 16 0 0 0 47 0 0 8 8 0 0 54 % S
% Thr: 0 8 0 8 0 0 8 0 8 8 0 0 8 8 0 % T
% Val: 0 0 0 8 0 8 0 8 8 0 0 47 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _