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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAD
All Species:
25.45
Human Site:
S1321
Identified Species:
62.22
UniProt:
P27708
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27708
NP_004332.2
2225
242984
S1321
N
I
L
L
T
I
G
S
Y
K
N
K
S
E
L
Chimpanzee
Pan troglodytes
XP_001155357
2225
242993
S1321
N
I
L
L
T
I
G
S
Y
K
N
K
S
E
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540124
2288
250188
S1367
N
I
L
L
T
I
G
S
Y
K
N
K
S
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C196
1500
164599
P705
N
I
Q
F
A
L
H
P
T
S
M
E
Y
C
I
Rat
Rattus norvegicus
P07756
1500
164561
P705
N
I
Q
F
A
L
H
P
T
S
M
E
Y
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001009884
2230
247184
S1326
N
I
L
L
S
I
G
S
Y
K
N
K
S
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05990
2224
246654
S1335
A
V
L
L
S
I
G
S
F
K
H
K
M
E
L
Honey Bee
Apis mellifera
XP_393888
2241
249499
S1335
G
I
L
L
S
I
G
S
F
K
H
K
M
E
L
Nematode Worm
Caenorhab. elegans
NP_495838
2198
242563
G1331
N
I
F
I
S
I
G
G
Y
H
A
K
A
E
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07259
2214
245107
S1369
N
I
L
L
S
I
G
S
Y
K
E
K
Q
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
94.8
N.A.
36.2
36.3
N.A.
N.A.
N.A.
N.A.
76.8
N.A.
64.5
63.6
57.8
N.A.
Protein Similarity:
100
100
N.A.
95.8
N.A.
48.5
48.6
N.A.
N.A.
N.A.
N.A.
86
N.A.
77.4
78
73.3
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
60
66.6
46.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
33.3
33.3
N.A.
N.A.
N.A.
N.A.
100
N.A.
86.6
86.6
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
69
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
20
0
0
0
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
20
0
80
0
% E
% Phe:
0
0
10
20
0
0
0
0
20
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
80
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
20
0
0
10
20
0
0
0
0
% H
% Ile:
0
90
0
10
0
80
0
0
0
0
0
0
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
70
0
80
0
0
0
% K
% Leu:
0
0
70
70
0
20
0
0
0
0
0
0
0
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
20
0
20
0
10
% M
% Asn:
80
0
0
0
0
0
0
0
0
0
40
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
0
0
20
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
50
0
0
70
0
20
0
0
40
0
0
% S
% Thr:
0
0
0
0
30
0
0
0
20
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
60
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _