KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAD
All Species:
29.09
Human Site:
Y678
Identified Species:
71.11
UniProt:
P27708
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27708
NP_004332.2
2225
242984
Y678
L
N
P
E
S
E
Q
Y
Y
I
I
E
V
N
A
Chimpanzee
Pan troglodytes
XP_001155357
2225
242993
Y678
L
N
P
E
S
E
Q
Y
Y
I
I
E
V
N
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540124
2288
250188
Y724
L
N
P
E
S
E
Q
Y
Y
I
I
E
V
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C196
1500
164599
A129
E
S
D
G
I
K
V
A
G
L
L
V
L
N
Y
Rat
Rattus norvegicus
P07756
1500
164561
A129
E
S
D
G
I
K
V
A
G
L
L
V
L
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001009884
2230
247184
Y680
L
N
P
E
S
E
Q
Y
Y
I
I
E
V
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05990
2224
246654
Y688
L
C
P
H
S
E
Q
Y
Y
I
I
E
V
N
A
Honey Bee
Apis mellifera
XP_393888
2241
249499
Y690
L
N
P
N
T
E
E
Y
Y
I
I
E
V
N
A
Nematode Worm
Caenorhab. elegans
NP_495838
2198
242563
Y675
L
D
P
Y
S
L
T
Y
Y
I
I
E
V
N
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07259
2214
245107
Y721
L
N
P
V
S
K
D
Y
C
I
I
E
V
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
94.8
N.A.
36.2
36.3
N.A.
N.A.
N.A.
N.A.
76.8
N.A.
64.5
63.6
57.8
N.A.
Protein Similarity:
100
100
N.A.
95.8
N.A.
48.5
48.6
N.A.
N.A.
N.A.
N.A.
86
N.A.
77.4
78
73.3
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
100
N.A.
86.6
80
73.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
40
40
N.A.
N.A.
N.A.
N.A.
100
N.A.
86.6
93.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
69
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
80
% A
% Cys:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
20
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
0
40
0
60
10
0
0
0
0
80
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
20
0
0
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
20
0
0
0
0
80
80
0
0
0
0
% I
% Lys:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% K
% Leu:
80
0
0
0
0
10
0
0
0
20
20
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
60
0
10
0
0
0
0
0
0
0
0
0
100
0
% N
% Pro:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
0
0
70
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
20
0
0
0
0
20
80
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
80
70
0
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _