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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALR
All Species:
48.79
Human Site:
S193
Identified Species:
71.56
UniProt:
P27797
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27797
NP_004334.1
417
48142
S193
I
D
N
S
Q
V
E
S
G
S
L
E
D
D
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110217
417
48095
S193
I
D
N
S
Q
V
E
S
G
S
L
E
D
D
W
Dog
Lupus familis
XP_853393
417
48162
S193
I
D
N
S
Q
V
E
S
G
S
L
E
D
D
W
Cat
Felis silvestris
Mouse
Mus musculus
P14211
416
47976
S193
I
D
N
S
Q
V
E
S
G
S
L
E
D
D
W
Rat
Rattus norvegicus
P18418
416
47977
S193
I
D
N
S
Q
V
E
S
G
S
L
E
D
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514084
419
48477
S194
I
D
N
S
K
V
E
S
G
T
L
E
S
D
W
Chicken
Gallus gallus
XP_418262
419
48016
L206
I
D
N
E
V
A
A
L
G
N
L
E
D
D
L
Frog
Xenopus laevis
NP_001080765
413
48503
S194
I
D
N
S
K
V
E
S
G
S
L
E
E
D
W
Zebra Danio
Brachydanio rerio
NP_956007
419
48936
S194
I
D
N
K
K
V
E
S
G
S
L
E
E
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
S193
I
D
N
E
K
V
E
S
G
N
L
E
D
D
W
Honey Bee
Apis mellifera
XP_392689
403
47156
S192
I
D
N
E
E
V
E
S
G
E
L
E
A
D
W
Nematode Worm
Caenorhab. elegans
P27798
395
45598
T188
I
D
G
E
S
A
Q
T
G
S
L
E
E
D
W
Sea Urchin
Strong. purpuratus
NP_999643
421
48804
A192
I
D
N
E
K
A
Q
A
G
N
L
E
E
D
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
T199
I
D
N
E
E
K
H
T
G
S
I
Y
E
H
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38858
424
48138
T196
I
D
N
V
E
K
Q
T
G
S
L
Y
S
D
W
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
M225
L
I
D
G
K
T
V
M
V
R
E
H
I
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
94.9
N.A.
94.2
93.7
N.A.
84
59.6
78.1
74.4
N.A.
64.2
66.9
62.5
64.8
Protein Similarity:
100
N.A.
99.7
97.3
N.A.
97.5
97.3
N.A.
92.3
73.9
90.1
85.9
N.A.
76.5
77.6
75.3
79.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
80
53.3
86.6
80
N.A.
80
73.3
53.3
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
60
100
93.3
N.A.
93.3
80
73.3
86.6
Percent
Protein Identity:
N.A.
52.1
N.A.
51.4
26.1
N.A.
Protein Similarity:
N.A.
70
N.A.
68.1
40.8
N.A.
P-Site Identity:
N.A.
40
N.A.
53.3
0
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
73.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
19
7
7
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
94
7
0
0
0
0
0
0
0
0
0
44
88
7
% D
% Glu:
0
0
0
38
19
0
63
0
0
7
7
82
32
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
7
0
0
0
0
94
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
7
0
7
0
% H
% Ile:
94
7
0
0
0
0
0
0
0
0
7
0
7
0
0
% I
% Lys:
0
0
0
7
38
13
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
0
0
7
0
0
88
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
88
0
0
0
0
0
0
19
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
32
0
19
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
0
0
44
7
0
0
63
0
63
0
0
13
0
0
% S
% Thr:
0
0
0
0
0
7
0
19
0
7
0
0
0
0
0
% T
% Val:
0
0
0
7
7
63
7
0
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
88
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _