Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CALR All Species: 33.33
Human Site: S44 Identified Species: 48.89
UniProt: P27797 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P27797 NP_004334.1 417 48142 S44 W I E S K H K S D F G K F V L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110217 417 48095 S44 W I E S K H K S D F G K F V L
Dog Lupus familis XP_853393 417 48162 S44 W I E S K H K S D F G K F V L
Cat Felis silvestris
Mouse Mus musculus P14211 416 47976 S44 W V E S K H K S D F G K F V L
Rat Rattus norvegicus P18418 416 47977 S44 W V E S K H K S D F G K F V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514084 419 48477 S45 W V E S K H K S D F G K F K L
Chicken Gallus gallus XP_418262 419 48016 P57 W V S S E S R P D L G T F Q L
Frog Xenopus laevis NP_001080765 413 48503 S45 W V E S K H K S D Y G K F K L
Zebra Danio Brachydanio rerio NP_956007 419 48936 T45 W V E S K H K T D Y G K F V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29413 406 46790 K44 I Y S K H P G K E F G K F V L
Honey Bee Apis mellifera XP_392689 403 47156 K43 V Y S E H P G K E F G K F I L
Nematode Worm Caenorhab. elegans P27798 395 45598 F41 Q S K H K D D F G A F K L S A
Sea Urchin Strong. purpuratus NP_999643 421 48804 S43 V E S V H K G S D A G K F K W
Poplar Tree Populus trichocarpa
Maize Zea mays Q9SP22 420 47921 E50 K S E W K K D E N M A G E W N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38858 424 48138 D47 K S E W K K D D N T A G E W K
Baker's Yeast Sacchar. cerevisiae P27825 502 56949 Y64 N N E G S K I Y G A Q W R L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 94.9 N.A. 94.2 93.7 N.A. 84 59.6 78.1 74.4 N.A. 64.2 66.9 62.5 64.8
Protein Similarity: 100 N.A. 99.7 97.3 N.A. 97.5 97.3 N.A. 92.3 73.9 90.1 85.9 N.A. 76.5 77.6 75.3 79.3
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 86.6 40 80 80 N.A. 40 33.3 13.3 33.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 60 93.3 100 N.A. 46.6 46.6 20 33.3
Percent
Protein Identity: N.A. 52.1 N.A. 51.4 26.1 N.A.
Protein Similarity: N.A. 70 N.A. 68.1 40.8 N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 20 N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 19 13 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 19 7 63 0 0 0 0 0 0 % D
% Glu: 0 7 69 7 7 0 0 7 13 0 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 50 7 0 75 0 0 % F
% Gly: 0 0 0 7 0 0 19 0 13 0 75 13 0 0 0 % G
% His: 0 0 0 7 19 50 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 19 0 0 0 0 7 0 0 0 0 0 0 7 0 % I
% Lys: 13 0 7 7 69 25 50 13 0 0 0 75 0 19 7 % K
% Leu: 0 0 0 0 0 0 0 0 0 7 0 0 7 7 69 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 0 0 0 13 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 13 0 7 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % R
% Ser: 0 19 25 57 7 7 0 50 0 0 0 0 0 7 7 % S
% Thr: 0 0 0 0 0 0 0 7 0 7 0 7 0 0 0 % T
% Val: 13 38 0 7 0 0 0 0 0 0 0 0 0 44 0 % V
% Trp: 57 0 0 13 0 0 0 0 0 0 0 7 0 13 7 % W
% Tyr: 0 13 0 0 0 0 0 7 0 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _