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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALR
All Species:
38.79
Human Site:
Y308
Identified Species:
56.89
UniProt:
P27797
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27797
NP_004334.1
417
48142
Y308
P
D
P
S
I
Y
A
Y
D
N
F
G
V
L
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110217
417
48095
Y308
P
D
P
S
I
Y
A
Y
D
N
F
G
V
L
G
Dog
Lupus familis
XP_853393
417
48162
Y308
P
D
S
N
I
Y
A
Y
E
N
F
A
V
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P14211
416
47976
Y308
P
D
A
N
I
Y
A
Y
D
S
F
A
V
L
G
Rat
Rattus norvegicus
P18418
416
47977
Y308
P
D
A
N
I
Y
A
Y
D
S
F
A
V
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514084
419
48477
Y309
P
D
S
N
L
Y
A
Y
D
S
F
G
V
L
G
Chicken
Gallus gallus
XP_418262
419
48016
Y321
P
D
Y
N
I
Y
S
Y
E
N
I
G
A
I
G
Frog
Xenopus laevis
NP_001080765
413
48503
Y309
P
D
S
T
L
Y
S
Y
E
S
F
G
V
I
G
Zebra Danio
Brachydanio rerio
NP_956007
419
48936
Y309
P
D
S
E
I
Y
K
Y
D
S
I
G
V
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
R308
P
D
D
K
L
Y
L
R
K
E
I
C
T
L
G
Honey Bee
Apis mellifera
XP_392689
403
47156
R307
P
D
P
E
L
Y
K
R
D
E
I
C
A
I
G
Nematode Worm
Caenorhab. elegans
P27798
395
45598
Y303
P
D
D
E
L
Y
S
Y
E
S
W
G
A
I
G
Sea Urchin
Strong. purpuratus
NP_999643
421
48804
Y307
A
D
E
N
L
Y
S
Y
P
S
F
G
A
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
F315
D
D
P
Y
I
Y
A
F
D
S
L
K
Y
I
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38858
424
48138
F312
D
D
P
E
L
Y
V
F
P
K
L
K
Y
V
G
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
I388
E
E
Q
H
P
L
R
I
E
N
V
I
S
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
94.9
N.A.
94.2
93.7
N.A.
84
59.6
78.1
74.4
N.A.
64.2
66.9
62.5
64.8
Protein Similarity:
100
N.A.
99.7
97.3
N.A.
97.5
97.3
N.A.
92.3
73.9
90.1
85.9
N.A.
76.5
77.6
75.3
79.3
P-Site Identity:
100
N.A.
100
73.3
N.A.
73.3
73.3
N.A.
73.3
53.3
53.3
60
N.A.
33.3
40
40
40
P-Site Similarity:
100
N.A.
100
86.6
N.A.
86.6
86.6
N.A.
93.3
80
93.3
73.3
N.A.
40
53.3
80
73.3
Percent
Protein Identity:
N.A.
52.1
N.A.
51.4
26.1
N.A.
Protein Similarity:
N.A.
70
N.A.
68.1
40.8
N.A.
P-Site Identity:
N.A.
46.6
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
13
0
0
0
44
0
0
0
0
19
25
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% C
% Asp:
13
94
13
0
0
0
0
0
50
0
0
0
0
0
0
% D
% Glu:
7
7
7
25
0
0
0
0
32
13
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
13
0
0
50
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
50
0
7
94
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
0
7
0
0
25
7
0
44
0
% I
% Lys:
0
0
0
7
0
0
13
0
7
7
0
13
0
0
0
% K
% Leu:
0
0
0
0
44
7
7
0
0
0
13
0
0
44
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
38
0
0
0
0
0
32
0
0
0
0
0
% N
% Pro:
75
0
32
0
7
0
0
0
13
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
13
0
0
0
0
0
0
0
% R
% Ser:
0
0
25
13
0
0
25
0
0
50
0
0
7
0
0
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
7
0
50
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
7
7
0
94
0
69
0
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _