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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CANX
All Species:
38.79
Human Site:
S259
Identified Species:
56.89
UniProt:
P27824
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27824
NP_001019820.1
592
67568
S259
V
D
Q
S
V
V
N
S
G
N
L
L
N
D
M
Chimpanzee
Pan troglodytes
XP_001151304
592
67554
S259
V
D
Q
S
V
V
N
S
G
N
L
L
N
D
M
Rhesus Macaque
Macaca mulatta
XP_001101429
592
67582
S259
V
D
Q
S
V
V
N
S
G
N
L
L
N
D
M
Dog
Lupus familis
XP_533285
610
69806
Q250
I
D
Q
V
V
V
N
Q
G
S
L
L
E
D
V
Cat
Felis silvestris
Mouse
Mus musculus
P35564
591
67259
S260
V
D
Q
S
V
V
N
S
G
N
L
L
N
D
M
Rat
Rattus norvegicus
P35565
591
67236
S260
V
D
Q
S
V
V
N
S
G
N
L
L
N
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506871
598
67609
S262
V
D
Q
T
V
V
N
S
G
N
L
L
N
D
M
Chicken
Gallus gallus
NP_001025791
599
68090
S260
V
D
Q
M
V
V
N
S
G
N
L
L
N
D
M
Frog
Xenopus laevis
NP_001080326
611
69964
R271
V
D
Q
T
V
V
N
R
G
S
L
L
N
D
M
Zebra Danio
Brachydanio rerio
NP_998613
600
67856
S267
I
D
Q
T
V
V
N
S
G
S
L
L
N
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
W200
S
G
N
L
E
D
D
W
D
F
L
A
P
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34652
619
69189
Y251
V
D
G
K
S
L
Y
Y
G
N
M
M
S
D
V
Sea Urchin
Strong. purpuratus
XP_791226
591
66512
S254
V
D
Q
K
V
V
N
S
G
S
L
L
S
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
I214
D
I
L
P
P
K
K
I
K
D
P
E
A
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29402
530
60468
D242
D
E
R
A
K
I
P
D
P
N
A
V
K
P
E
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
P256
P
D
V
S
V
A
K
P
H
D
W
D
D
R
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
59.1
N.A.
93
93.5
N.A.
85.7
82.8
78.2
70.8
N.A.
31.7
N.A.
40.5
53.7
Protein Similarity:
100
99.8
99.4
75.2
N.A.
96.6
97.4
N.A.
93.1
90.8
86.2
84.1
N.A.
44.7
N.A.
58.9
69.7
P-Site Identity:
100
100
100
60
N.A.
100
100
N.A.
93.3
93.3
80
73.3
N.A.
6.6
N.A.
33.3
80
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
100
93.3
93.3
100
N.A.
13.3
N.A.
66.6
93.3
Percent
Protein Identity:
N.A.
29.3
N.A.
40
25.6
N.A.
Protein Similarity:
N.A.
44.4
N.A.
53.5
41.2
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
0
0
0
0
7
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
82
0
0
0
7
7
7
7
13
0
7
7
75
0
% D
% Glu:
0
7
0
0
7
0
0
0
0
0
0
7
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
0
0
0
75
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
13
7
0
0
0
7
0
7
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
13
7
7
13
0
7
0
0
0
7
13
13
% K
% Leu:
0
0
7
7
0
7
0
0
0
0
75
69
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
7
7
0
0
57
% M
% Asn:
0
0
7
0
0
0
69
0
0
57
0
0
57
0
0
% N
% Pro:
7
0
0
7
7
0
7
7
7
0
7
0
7
7
0
% P
% Gln:
0
0
69
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
7
0
0
0
0
0
7
0
% R
% Ser:
7
0
0
38
7
0
0
57
0
25
0
0
13
0
0
% S
% Thr:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
63
0
7
7
75
69
0
0
0
0
0
7
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _