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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CANX
All Species:
16.97
Human Site:
T49
Identified Species:
24.89
UniProt:
P27824
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27824
NP_001019820.1
592
67568
T49
V
E
D
S
K
P
D
T
T
A
P
P
S
S
P
Chimpanzee
Pan troglodytes
XP_001151304
592
67554
T49
V
E
D
S
K
P
D
T
T
A
P
P
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001101429
592
67582
T49
V
E
D
S
K
P
D
T
T
A
P
P
S
S
P
Dog
Lupus familis
XP_533285
610
69806
V40
E
N
S
E
E
I
D
V
N
E
G
E
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P35564
591
67259
D50
E
D
S
K
S
K
S
D
A
S
T
P
P
S
P
Rat
Rattus norvegicus
P35565
591
67236
D50
E
D
S
K
S
K
S
D
T
S
T
P
P
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506871
598
67609
A52
G
E
D
T
K
P
E
A
S
S
P
P
P
S
P
Chicken
Gallus gallus
NP_001025791
599
68090
S50
I
E
D
S
N
P
E
S
S
T
P
P
P
A
P
Frog
Xenopus laevis
NP_001080326
611
69964
T61
P
E
E
L
K
P
E
T
S
M
P
P
P
A
P
Zebra Danio
Brachydanio rerio
NP_998613
600
67856
A57
I
E
E
E
E
Q
K
A
P
A
P
P
S
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34652
619
69189
E41
T
K
G
S
D
D
K
E
E
F
V
P
S
L
F
Sea Urchin
Strong. purpuratus
XP_791226
591
66512
D44
V
Q
V
E
E
E
E
D
V
E
P
I
E
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29402
530
60468
Y32
C
D
D
Q
T
V
L
Y
E
S
F
D
E
P
F
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
L46
A
Y
T
N
T
K
H
L
N
Q
E
W
I
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
59.1
N.A.
93
93.5
N.A.
85.7
82.8
78.2
70.8
N.A.
31.7
N.A.
40.5
53.7
Protein Similarity:
100
99.8
99.4
75.2
N.A.
96.6
97.4
N.A.
93.1
90.8
86.2
84.1
N.A.
44.7
N.A.
58.9
69.7
P-Site Identity:
100
100
100
6.6
N.A.
20
26.6
N.A.
53.3
46.6
46.6
40
N.A.
0
N.A.
20
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
33.3
40
N.A.
80
80
73.3
66.6
N.A.
0
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
29.3
N.A.
40
25.6
N.A.
Protein Similarity:
N.A.
44.4
N.A.
53.5
41.2
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
0
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
13
7
25
0
0
0
19
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
38
0
7
7
25
19
0
0
0
7
0
0
0
% D
% Glu:
19
44
13
19
19
7
25
7
13
13
7
7
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
13
% F
% Gly:
7
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
7
0
0
0
0
0
7
7
0
0
% I
% Lys:
0
7
0
13
32
19
13
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
0
7
7
0
0
0
0
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
7
7
0
0
0
13
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
38
0
0
7
0
50
63
32
13
57
% P
% Gln:
0
7
0
7
0
7
0
0
0
7
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
19
32
13
0
13
7
19
25
0
0
32
38
13
% S
% Thr:
7
0
7
7
13
0
0
25
25
7
13
0
0
7
0
% T
% Val:
25
0
7
0
0
7
0
7
7
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _