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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKB
All Species:
7.88
Human Site:
S246
Identified Species:
15.76
UniProt:
P27987
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27987
NP_002212.3
946
102376
S246
G
R
A
A
P
T
G
S
E
A
Q
G
P
S
A
Chimpanzee
Pan troglodytes
XP_001141610
946
102163
S246
G
R
A
A
P
T
G
S
E
A
Q
G
P
S
A
Rhesus Macaque
Macaca mulatta
XP_001089824
939
101522
S243
G
R
G
A
P
T
G
S
E
A
W
G
P
F
V
Dog
Lupus familis
XP_547504
936
98978
P242
G
P
A
A
L
S
E
P
G
A
R
G
A
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
R30
R
M
G
L
E
A
L
R
G
G
R
R
R
Q
P
Rat
Rattus norvegicus
P42335
934
101801
L251
G
P
A
S
P
T
R
L
G
T
Q
S
P
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513057
370
41159
Chicken
Gallus gallus
XP_415039
637
69972
Frog
Xenopus laevis
NP_001088157
516
58252
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
L9
A
A
Y
A
L
N
S
L
I
M
M
N
P
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
Q21
K
S
N
Q
N
Q
K
Q
K
N
G
P
A
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
73.7
N.A.
34.4
76.2
N.A.
31.7
51.1
32.6
44.9
N.A.
32.6
N.A.
N.A.
25.2
Protein Similarity:
100
99
95.1
79.1
N.A.
46.7
80.9
N.A.
34.1
57
41.6
54.1
N.A.
46.2
N.A.
N.A.
30
P-Site Identity:
100
100
73.3
40
N.A.
0
46.6
N.A.
0
0
0
13.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
73.3
60
N.A.
6.6
53.3
N.A.
0
0
0
20
N.A.
6.6
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
34
42
0
9
0
0
0
34
0
0
17
9
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
9
0
25
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
42
0
17
0
0
0
25
0
25
9
9
34
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
17
0
9
17
0
0
0
0
0
0
9
% L
% Met:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
0
% M
% Asn:
0
0
9
0
9
9
0
0
0
9
0
9
0
9
9
% N
% Pro:
0
17
0
0
34
0
0
9
0
0
0
9
42
0
9
% P
% Gln:
0
0
0
9
0
9
0
9
0
0
25
0
0
9
0
% Q
% Arg:
9
25
0
0
0
0
9
9
0
0
17
9
9
9
0
% R
% Ser:
0
9
0
9
0
9
9
25
0
0
0
9
0
25
0
% S
% Thr:
0
0
0
0
0
34
0
0
0
9
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _