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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKB
All Species:
9.7
Human Site:
S440
Identified Species:
19.39
UniProt:
P27987
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27987
NP_002212.3
946
102376
S440
G
G
G
R
W
Q
L
S
D
R
V
E
G
G
S
Chimpanzee
Pan troglodytes
XP_001141610
946
102163
S440
G
G
G
R
W
Q
L
S
D
R
V
E
G
G
S
Rhesus Macaque
Macaca mulatta
XP_001089824
939
101522
S435
G
R
G
R
W
Q
L
S
D
R
V
E
G
G
S
Dog
Lupus familis
XP_547504
936
98978
A439
P
P
Q
H
S
R
G
A
D
E
G
S
L
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
P208
V
S
K
L
Q
T
H
P
V
C
L
S
P
E
S
Rat
Rattus norvegicus
P42335
934
101801
L431
I
R
G
P
Q
Q
T
L
D
S
M
R
E
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513057
370
41159
Chicken
Gallus gallus
XP_415039
637
69972
R167
S
P
R
L
S
S
P
R
P
S
S
P
R
P
S
Frog
Xenopus laevis
NP_001088157
516
58252
H46
R
Q
N
S
Q
P
L
H
L
P
I
K
Q
Q
W
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
T187
T
R
N
K
D
H
S
T
G
I
P
K
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
Q199
K
C
S
L
A
F
A
Q
A
H
G
I
R
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
73.7
N.A.
34.4
76.2
N.A.
31.7
51.1
32.6
44.9
N.A.
32.6
N.A.
N.A.
25.2
Protein Similarity:
100
99
95.1
79.1
N.A.
46.7
80.9
N.A.
34.1
57
41.6
54.1
N.A.
46.2
N.A.
N.A.
30
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
33.3
N.A.
0
6.6
6.6
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
20
N.A.
13.3
40
N.A.
0
6.6
20
20
N.A.
0
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
9
9
9
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
42
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
25
17
9
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
25
17
34
0
0
0
9
0
9
0
17
0
25
34
0
% G
% His:
0
0
0
9
0
9
9
9
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
9
9
0
0
0
% I
% Lys:
9
0
9
9
0
0
0
0
0
0
0
17
0
0
0
% K
% Leu:
0
0
0
25
0
0
34
9
9
0
9
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
17
0
9
0
9
9
9
9
9
9
9
9
9
9
% P
% Gln:
0
9
9
0
25
34
0
9
0
0
0
0
9
17
9
% Q
% Arg:
9
25
9
25
0
9
0
9
0
25
0
9
17
0
9
% R
% Ser:
9
9
9
9
17
9
9
25
0
17
9
17
0
0
50
% S
% Thr:
9
0
0
0
0
9
9
9
0
0
0
0
0
9
0
% T
% Val:
9
0
0
0
0
0
0
0
9
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _