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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKB
All Species:
17.58
Human Site:
S588
Identified Species:
35.15
UniProt:
P27987
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27987
NP_002212.3
946
102376
S588
A
L
E
E
T
Q
G
S
P
R
G
N
L
P
L
Chimpanzee
Pan troglodytes
XP_001141610
946
102163
S588
A
L
E
E
T
Q
G
S
P
R
G
N
L
P
L
Rhesus Macaque
Macaca mulatta
XP_001089824
939
101522
S583
A
L
E
E
T
Q
G
S
P
R
G
N
L
P
L
Dog
Lupus familis
XP_547504
936
98978
S578
T
L
E
D
P
Q
G
S
P
R
G
S
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
E334
T
P
E
T
P
E
P
E
A
Q
P
V
G
P
Q
Rat
Rattus norvegicus
P42335
934
101801
S576
G
L
E
E
I
Q
G
S
P
R
G
P
L
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513057
370
41159
A26
Q
V
F
R
G
P
G
A
R
P
Q
P
P
P
W
Chicken
Gallus gallus
XP_415039
637
69972
S293
V
R
K
L
S
S
S
S
A
S
S
T
G
F
S
Frog
Xenopus laevis
NP_001088157
516
58252
F172
G
S
P
V
P
S
L
F
I
R
K
L
S
S
S
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
R313
E
V
S
P
Q
T
N
R
T
L
R
K
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
A325
T
G
S
G
S
G
A
A
S
Q
A
S
T
T
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
M12
T
N
N
G
S
L
N
M
M
D
V
S
N
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
73.7
N.A.
34.4
76.2
N.A.
31.7
51.1
32.6
44.9
N.A.
32.6
N.A.
N.A.
25.2
Protein Similarity:
100
99
95.1
79.1
N.A.
46.7
80.9
N.A.
34.1
57
41.6
54.1
N.A.
46.2
N.A.
N.A.
30
P-Site Identity:
100
100
100
73.3
N.A.
13.3
80
N.A.
13.3
6.6
6.6
6.6
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
26.6
80
N.A.
26.6
20
6.6
13.3
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
0
9
17
17
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
9
0
50
34
0
9
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
9
0
0
0
0
0
9
0
% F
% Gly:
17
9
0
17
9
9
50
0
0
0
42
0
17
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% K
% Leu:
0
42
0
9
0
9
9
0
0
9
0
9
50
0
42
% L
% Met:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
17
0
0
0
0
25
9
9
0
% N
% Pro:
0
9
9
9
25
9
9
0
42
9
9
17
9
59
0
% P
% Gln:
9
0
0
0
9
42
0
0
0
17
9
0
0
0
9
% Q
% Arg:
0
9
0
9
0
0
0
9
9
50
9
0
0
0
0
% R
% Ser:
0
9
17
0
25
17
9
50
9
9
9
25
9
17
34
% S
% Thr:
34
0
0
9
25
9
0
0
9
0
0
9
9
9
0
% T
% Val:
9
17
0
9
0
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _