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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPKB All Species: 22.42
Human Site: S927 Identified Species: 44.85
UniProt: P27987 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P27987 NP_002212.3 946 102376 S927 N R E D G Y L S G L N N L V D
Chimpanzee Pan troglodytes XP_001141610 946 102163 S927 N R E D G Y L S G L N N L I D
Rhesus Macaque Macaca mulatta XP_001089824 939 101522 S920 N R E D G Y L S G L N N L I D
Dog Lupus familis XP_547504 936 98978 S917 N R E D G Y L S G L N N L I D
Cat Felis silvestris
Mouse Mus musculus Q7TS72 678 74474 G660 T E G N R E D G Y L W G L D N
Rat Rattus norvegicus P42335 934 101801 S915 N R E D G Y L S G L N N L I D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513057 370 41159 P352 L Q A P H T N P S L L S G L G
Chicken Gallus gallus XP_415039 637 69972 G619 R E D G Y L W G L D N L I Q I
Frog Xenopus laevis NP_001088157 516 58252 G498 V E G N R E D G Y L W G L D N
Zebra Danio Brachydanio rerio XP_691475 657 73298 Y639 N R E D G Y L Y G L D H L I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572875 669 73198 P651 Q A E A I Q S P V S G S G G D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795627 356 40840 G338 H E D G Y L Y G L D Q M I Q V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 93.6 73.7 N.A. 34.4 76.2 N.A. 31.7 51.1 32.6 44.9 N.A. 32.6 N.A. N.A. 25.2
Protein Similarity: 100 99 95.1 79.1 N.A. 46.7 80.9 N.A. 34.1 57 41.6 54.1 N.A. 46.2 N.A. N.A. 30
P-Site Identity: 100 93.3 93.3 93.3 N.A. 13.3 93.3 N.A. 6.6 6.6 13.3 73.3 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 26.6 100 N.A. 26.6 20 26.6 93.3 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 17 50 0 0 17 0 0 17 9 0 0 17 59 % D
% Glu: 0 34 59 0 0 17 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 17 50 0 0 34 50 0 9 17 17 9 9 % G
% His: 9 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 17 42 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 0 17 50 0 17 75 9 9 67 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 50 0 0 17 0 0 9 0 0 0 50 42 0 0 17 % N
% Pro: 0 0 0 9 0 0 0 17 0 0 0 0 0 0 0 % P
% Gln: 9 9 0 0 0 9 0 0 0 0 9 0 0 17 0 % Q
% Arg: 9 50 0 0 17 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 9 42 9 9 0 17 0 0 0 % S
% Thr: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 9 0 0 0 0 0 0 0 9 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 17 0 0 0 0 % W
% Tyr: 0 0 0 0 17 50 9 9 17 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _