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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKB
All Species:
18.79
Human Site:
Y612
Identified Species:
37.58
UniProt:
P27987
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27987
NP_002212.3
946
102376
Y612
S
T
G
F
S
S
S
Y
E
D
S
E
E
D
I
Chimpanzee
Pan troglodytes
XP_001141610
946
102163
Y612
S
T
G
F
S
S
S
Y
E
D
S
E
E
D
I
Rhesus Macaque
Macaca mulatta
XP_001089824
939
101522
Y607
S
T
G
F
S
S
S
Y
E
D
S
E
E
D
I
Dog
Lupus familis
XP_547504
936
98978
Y602
S
T
G
F
S
S
S
Y
E
D
S
E
E
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
D358
F
S
S
A
S
S
F
D
E
S
E
D
D
L
V
Rat
Rattus norvegicus
P42335
934
101801
Y600
S
T
G
F
S
S
S
Y
E
D
S
E
E
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513057
370
41159
A50
C
C
P
G
N
I
P
A
V
I
I
T
D
T
G
Chicken
Gallus gallus
XP_415039
637
69972
T317
I
S
S
D
P
E
R
T
L
D
Q
A
P
A
F
Frog
Xenopus laevis
NP_001088157
516
58252
G196
E
E
S
E
D
D
F
G
G
S
D
M
E
P
N
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
D337
S
S
W
E
E
S
E
D
D
I
S
S
D
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
P349
R
N
I
V
Q
W
T
P
F
F
Q
T
Y
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
C36
D
D
S
L
L
D
E
C
T
R
I
C
M
C
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
73.7
N.A.
34.4
76.2
N.A.
31.7
51.1
32.6
44.9
N.A.
32.6
N.A.
N.A.
25.2
Protein Similarity:
100
99
95.1
79.1
N.A.
46.7
80.9
N.A.
34.1
57
41.6
54.1
N.A.
46.2
N.A.
N.A.
30
P-Site Identity:
100
100
100
100
N.A.
20
100
N.A.
0
6.6
6.6
20
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
46.6
100
N.A.
13.3
13.3
6.6
40
N.A.
6.6
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
0
0
0
9
0
9
0
% A
% Cys:
9
9
0
0
0
0
0
9
0
0
0
9
0
9
0
% C
% Asp:
9
9
0
9
9
17
0
17
9
50
9
9
25
42
9
% D
% Glu:
9
9
0
17
9
9
17
0
50
0
9
42
50
0
9
% E
% Phe:
9
0
0
42
0
0
17
0
9
9
0
0
0
0
9
% F
% Gly:
0
0
42
9
0
0
0
9
9
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
0
0
9
0
0
0
17
17
0
0
0
42
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% K
% Leu:
0
0
0
9
9
0
0
0
9
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% M
% Asn:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
9
0
9
0
9
9
0
0
0
0
9
17
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
17
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% R
% Ser:
50
25
34
0
50
59
42
0
0
17
50
9
0
0
0
% S
% Thr:
0
42
0
0
0
0
9
9
9
0
0
17
0
9
0
% T
% Val:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _