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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HLA-DMB All Species: 12.73
Human Site: S185 Identified Species: 40
UniProt: P28068 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.43
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28068 NP_002109.1 263 28943 S185 S H L A L T P S Y G D T Y T C
Chimpanzee Pan troglodytes P18467 273 30903 E192 V M L E M T P E L G H V Y T C
Rhesus Macaque Macaca mulatta XP_001115584 295 32577 S217 S Y L A L T P S Y G D T Y T C
Dog Lupus familis XP_849737 263 28873 S185 S H L A T T P S Y E D T Y T C
Cat Felis silvestris
Mouse Mus musculus P35737 261 28881 S185 S Y L A L T P S Y G D V Y T C
Rat Rattus norvegicus P06341 233 26809 E158 F Q I L V M L E M T P Q R G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P23068 231 26259 E156 Y Q V L V V L E I S P R H G D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001083028 252 28392 H177 G D W Y Y Q I H S H L E Y T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.3 80 77.9 N.A. 71.8 22.8 N.A. N.A. 25.1 N.A. 28.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 41.3 83.3 86.6 N.A. 82.5 38.4 N.A. N.A. 41 N.A. 46.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 46.6 93.3 86.6 N.A. 86.6 0 N.A. N.A. 0 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 53.3 100 86.6 N.A. 93.3 13.3 N.A. N.A. 20 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 % C
% Asp: 0 13 0 0 0 0 0 0 0 0 50 0 0 0 25 % D
% Glu: 0 0 0 13 0 0 0 38 0 13 0 13 0 0 0 % E
% Phe: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 0 0 0 0 0 0 0 0 50 0 0 0 25 0 % G
% His: 0 25 0 0 0 0 0 13 0 13 13 0 13 0 0 % H
% Ile: 0 0 13 0 0 0 13 0 13 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 63 25 38 0 25 0 13 0 13 0 0 0 0 % L
% Met: 0 13 0 0 13 13 0 0 13 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 63 0 0 0 25 0 0 0 13 % P
% Gln: 0 25 0 0 0 13 0 0 0 0 0 13 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 13 13 0 0 % R
% Ser: 50 0 0 0 0 0 0 50 13 13 0 0 0 0 0 % S
% Thr: 0 0 0 0 13 63 0 0 0 13 0 38 0 75 0 % T
% Val: 13 0 13 0 25 13 0 0 0 0 0 25 0 0 0 % V
% Trp: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 25 0 13 13 0 0 0 50 0 0 0 75 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _