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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLA-DMB
All Species:
16.36
Human Site:
Y190
Identified Species:
51.43
UniProt:
P28068
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28068
NP_002109.1
263
28943
Y190
T
P
S
Y
G
D
T
Y
T
C
V
V
E
H
I
Chimpanzee
Pan troglodytes
P18467
273
30903
Y197
T
P
E
L
G
H
V
Y
T
C
L
V
D
H
S
Rhesus Macaque
Macaca mulatta
XP_001115584
295
32577
Y222
T
P
S
Y
G
D
T
Y
T
C
V
V
E
H
I
Dog
Lupus familis
XP_849737
263
28873
Y190
T
P
S
Y
E
D
T
Y
T
C
V
V
E
H
I
Cat
Felis silvestris
Mouse
Mus musculus
P35737
261
28881
Y190
T
P
S
Y
G
D
V
Y
T
C
V
V
Q
H
S
Rat
Rattus norvegicus
P06341
233
26809
R163
M
L
E
M
T
P
Q
R
G
D
V
Y
T
C
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23068
231
26259
H161
V
L
E
I
S
P
R
H
G
D
S
Y
V
C
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001083028
252
28392
Y182
Q
I
H
S
H
L
E
Y
T
P
K
S
G
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
80
77.9
N.A.
71.8
22.8
N.A.
N.A.
25.1
N.A.
28.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.3
83.3
86.6
N.A.
82.5
38.4
N.A.
N.A.
41
N.A.
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
93.3
N.A.
80
6.6
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
93.3
N.A.
86.6
6.6
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
63
0
0
0
25
0
% C
% Asp:
0
0
0
0
0
50
0
0
0
25
0
0
13
0
0
% D
% Glu:
0
0
38
0
13
0
13
0
0
0
0
0
38
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
50
0
0
0
25
0
0
0
13
0
0
% G
% His:
0
0
13
0
13
13
0
13
0
0
0
0
0
63
13
% H
% Ile:
0
13
0
13
0
0
0
0
0
0
0
0
0
0
38
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
13
% K
% Leu:
0
25
0
13
0
13
0
0
0
0
13
0
0
0
0
% L
% Met:
13
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
63
0
0
0
25
0
0
0
13
0
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
13
0
0
0
0
0
13
0
13
% Q
% Arg:
0
0
0
0
0
0
13
13
0
0
0
0
0
0
0
% R
% Ser:
0
0
50
13
13
0
0
0
0
0
13
13
0
0
25
% S
% Thr:
63
0
0
0
13
0
38
0
75
0
0
0
13
0
0
% T
% Val:
13
0
0
0
0
0
25
0
0
0
63
63
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
75
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _