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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU1F1
All Species:
32.73
Human Site:
S275
Identified Species:
55.38
UniProt:
P28069
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28069
NP_000297.1
291
32912
S275
R
E
K
R
V
K
T
S
L
N
Q
S
L
F
S
Chimpanzee
Pan troglodytes
XP_526244
291
32921
S275
R
E
K
R
V
K
T
S
L
N
Q
N
L
F
S
Rhesus Macaque
Macaca mulatta
Q28503
291
32940
S275
R
E
K
R
V
K
T
S
L
N
Q
S
L
F
S
Dog
Lupus familis
XP_549108
361
39472
P339
K
E
K
R
M
T
P
P
G
D
Q
Q
P
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q00286
291
32867
S275
R
E
K
R
V
K
T
S
L
N
Q
S
L
F
S
Rat
Rattus norvegicus
P10037
291
32885
S275
R
E
K
R
V
K
T
S
L
N
Q
S
L
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515178
338
38300
S321
R
E
K
R
V
K
T
S
L
H
Q
N
T
F
T
Chicken
Gallus gallus
Q9YGL7
363
40431
S346
R
E
K
R
V
K
T
S
L
H
Q
N
A
F
S
Frog
Xenopus laevis
P31363
375
41827
P346
Q
K
E
K
R
M
T
P
A
G
V
P
H
P
P
Zebra Danio
Brachydanio rerio
P79745
443
47434
T389
R
Q
K
E
K
R
M
T
P
P
G
V
P
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16241
427
45909
T363
R
Q
K
E
K
R
M
T
P
P
N
T
L
G
G
Honey Bee
Apis mellifera
XP_393686
460
49306
T400
R
Q
K
E
K
R
M
T
P
P
N
T
L
G
D
Nematode Worm
Caenorhab. elegans
P20268
380
42556
N342
K
E
K
R
I
A
P
N
Q
Y
D
A
P
H
P
Sea Urchin
Strong. purpuratus
XP_782909
467
49786
P372
K
E
K
R
M
T
P
P
L
N
G
I
G
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
35.1
N.A.
95.5
95.8
N.A.
66.2
70.2
34.9
30.2
N.A.
31.3
30.2
34.2
29.5
Protein Similarity:
100
100
98.9
48.7
N.A.
97.9
97.9
N.A.
73
75.7
50.4
44.9
N.A.
45.4
43.9
46.3
41.5
P-Site Identity:
100
93.3
100
26.6
N.A.
100
100
N.A.
73.3
80
6.6
13.3
N.A.
20
20
20
33.3
P-Site Similarity:
100
100
100
46.6
N.A.
100
100
N.A.
93.3
93.3
33.3
40
N.A.
46.6
46.6
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% D
% Glu:
0
72
8
22
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
15
0
8
15
15
% G
% His:
0
0
0
0
0
0
0
0
0
15
0
0
8
15
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
22
8
93
8
22
50
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
58
0
0
0
50
0
0
% L
% Met:
0
0
0
0
15
8
22
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
43
15
22
0
0
0
% N
% Pro:
0
0
0
0
0
0
22
22
22
22
0
8
22
15
15
% P
% Gln:
8
22
0
0
0
0
0
0
8
0
58
8
0
8
0
% Q
% Arg:
72
0
0
72
8
22
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
29
0
0
43
% S
% Thr:
0
0
0
0
0
15
58
22
0
0
0
15
8
0
15
% T
% Val:
0
0
0
0
50
0
0
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _