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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POU1F1
All Species:
27.27
Human Site:
T219
Identified Species:
46.15
UniProt:
P28069
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.54
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28069
NP_000297.1
291
32912
T219
E
R
K
R
K
R
R
T
T
I
S
I
A
A
K
Chimpanzee
Pan troglodytes
XP_526244
291
32921
T219
E
R
K
R
K
R
R
T
T
I
S
I
A
A
K
Rhesus Macaque
Macaca mulatta
Q28503
291
32940
T219
E
R
K
R
K
R
R
T
T
I
S
I
A
A
K
Dog
Lupus familis
XP_549108
361
39472
K281
A
Q
G
R
K
R
K
K
R
T
S
I
E
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q00286
291
32867
T219
E
R
K
R
K
R
R
T
T
I
S
V
A
A
K
Rat
Rattus norvegicus
P10037
291
32885
T219
E
R
K
R
K
R
R
T
T
I
S
I
A
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515178
338
38300
T265
E
R
K
R
K
R
R
T
T
I
S
I
A
A
K
Chicken
Gallus gallus
Q9YGL7
363
40431
T290
E
R
K
R
K
R
R
T
T
I
S
I
S
A
K
Frog
Xenopus laevis
P31363
375
41827
K289
A
Q
G
R
K
R
K
K
R
T
S
I
E
V
G
Zebra Danio
Brachydanio rerio
P79745
443
47434
K333
A
Q
G
R
K
R
K
K
R
T
S
I
E
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16241
427
45909
K307
A
Q
G
R
K
R
K
K
R
T
S
I
E
V
S
Honey Bee
Apis mellifera
XP_393686
460
49306
K344
A
Q
G
R
K
R
K
K
R
T
S
I
E
V
S
Nematode Worm
Caenorhab. elegans
P20268
380
42556
R282
T
G
Q
A
G
R
K
R
K
K
R
T
S
I
E
Sea Urchin
Strong. purpuratus
XP_782909
467
49786
K314
A
Q
G
R
K
R
K
K
R
T
S
I
E
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
35.1
N.A.
95.5
95.8
N.A.
66.2
70.2
34.9
30.2
N.A.
31.3
30.2
34.2
29.5
Protein Similarity:
100
100
98.9
48.7
N.A.
97.9
97.9
N.A.
73
75.7
50.4
44.9
N.A.
45.4
43.9
46.3
41.5
P-Site Identity:
100
100
100
33.3
N.A.
93.3
100
N.A.
100
93.3
33.3
33.3
N.A.
33.3
33.3
6.6
33.3
P-Site Similarity:
100
100
100
46.6
N.A.
100
100
N.A.
100
100
46.6
46.6
N.A.
46.6
46.6
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
0
8
0
0
0
0
0
0
0
0
43
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
0
0
0
0
0
0
0
0
0
0
0
43
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
43
0
8
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
50
0
86
0
8
0
% I
% Lys:
0
0
50
0
93
0
50
43
8
8
0
0
0
0
50
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
43
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
50
0
93
0
100
50
8
43
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
93
0
15
0
29
% S
% Thr:
8
0
0
0
0
0
0
50
50
43
0
8
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
43
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _