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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POU1F1 All Species: 19.09
Human Site: T66 Identified Species: 32.31
UniProt: P28069 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28069 NP_000297.1 291 32912 T66 H Y G N Q P S T Y G V M A G S
Chimpanzee Pan troglodytes XP_526244 291 32921 T66 H Y G N Q P S T Y G V M A G S
Rhesus Macaque Macaca mulatta Q28503 291 32940 T66 H Y G N Q P S T Y G V M A G S
Dog Lupus familis XP_549108 361 39472 S68 L G D G G P W S S T L A T N P
Cat Felis silvestris
Mouse Mus musculus Q00286 291 32867 T66 H Y G N Q P S T Y G V M A G S
Rat Rattus norvegicus P10037 291 32885 T66 H Y G N Q P S T Y G V M A G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515178 338 38300 G112 S H P S V V N G V S A L Q G S
Chicken Gallus gallus Q9YGL7 363 40431 A66 K C S H F H F A M M T S G N V
Frog Xenopus laevis P31363 375 41827 P130 H H L A P M S P S S N S H Q P
Zebra Danio Brachydanio rerio P79745 443 47434 A149 P H Q T H A G A W G S T T A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16241 427 45909 N69 P S P N G Q G N G G G L G L G
Honey Bee Apis mellifera XP_393686 460 49306 P88 A S L S S A N P W V S L Q P S
Nematode Worm Caenorhab. elegans P20268 380 42556 A66 V I K P T C E A F Q D W P H T
Sea Urchin Strong. purpuratus XP_782909 467 49786 H102 H W A G V P A H L L G H G Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.9 35.1 N.A. 95.5 95.8 N.A. 66.2 70.2 34.9 30.2 N.A. 31.3 30.2 34.2 29.5
Protein Similarity: 100 100 98.9 48.7 N.A. 97.9 97.9 N.A. 73 75.7 50.4 44.9 N.A. 45.4 43.9 46.3 41.5
P-Site Identity: 100 100 100 6.6 N.A. 100 93.3 N.A. 13.3 0 13.3 6.6 N.A. 13.3 6.6 0 13.3
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. 40 6.6 20 26.6 N.A. 20 33.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 15 8 22 0 0 8 8 36 8 8 % A
% Cys: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 0 8 0 8 0 0 0 0 0 0 % F
% Gly: 0 8 36 15 15 0 15 8 8 50 15 0 22 43 8 % G
% His: 50 22 0 8 8 8 0 8 0 0 0 8 8 8 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 15 0 0 0 0 0 8 8 8 22 0 8 0 % L
% Met: 0 0 0 0 0 8 0 0 8 8 0 36 0 0 0 % M
% Asn: 0 0 0 43 0 0 15 8 0 0 8 0 0 15 0 % N
% Pro: 15 0 15 8 8 50 0 15 0 0 0 0 8 8 15 % P
% Gln: 0 0 8 0 36 8 0 0 0 8 0 0 15 15 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 15 8 15 8 0 43 8 15 15 15 15 0 0 43 % S
% Thr: 0 0 0 8 8 0 0 36 0 8 8 8 15 0 15 % T
% Val: 8 0 0 0 15 8 0 0 8 8 36 0 0 0 8 % V
% Trp: 0 8 0 0 0 0 8 0 15 0 0 8 0 0 0 % W
% Tyr: 0 36 0 0 0 0 0 0 36 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _