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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR1D
All Species:
10
Human Site:
S233
Identified Species:
22
UniProt:
P28221
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28221
NP_000855.1
377
41907
S233
N
R
I
L
N
P
P
S
L
Y
G
K
R
F
T
Chimpanzee
Pan troglodytes
Q9N2D9
365
41472
S233
N
G
Q
V
L
L
E
S
G
E
K
S
T
K
S
Rhesus Macaque
Macaca mulatta
XP_001102386
377
42020
S233
N
R
I
L
N
P
P
S
L
Y
G
K
R
F
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q61224
374
41521
Y232
I
L
N
P
P
S
L
Y
G
K
R
F
T
T
A
Rat
Rattus norvegicus
P28565
374
41521
Y232
I
L
N
P
P
S
L
Y
G
K
R
F
T
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514834
364
39461
K232
R
P
S
A
L
A
G
K
R
F
T
T
A
Q
L
Chicken
Gallus gallus
XP_001232312
378
42181
S233
S
R
I
L
K
P
P
S
L
Y
G
K
R
F
T
Frog
Xenopus laevis
Q98998
408
45769
Q264
E
V
G
G
A
Q
A
Q
R
C
V
N
G
A
I
Zebra Danio
Brachydanio rerio
NP_001139158
386
42451
N243
T
A
A
Q
L
I
Q
N
S
A
G
S
S
L
C
Tiger Blowfish
Takifugu rubipres
O42384
416
47013
R233
F
R
I
R
R
T
V
R
K
T
E
K
K
K
V
Fruit Fly
Dros. melanogaster
P20905
564
60843
R358
R
I
V
L
E
E
K
R
A
Q
T
H
L
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
97.3
N.A.
N.A.
90.4
90.1
N.A.
65.5
79.8
40.2
67.3
40.8
30.6
N.A.
N.A.
N.A.
Protein Similarity:
100
63.4
98.4
N.A.
N.A.
93
93.3
N.A.
78.5
88.6
57.3
80
58.4
43.7
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
N.A.
N.A.
0
0
N.A.
0
86.6
0
6.6
20
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
N.A.
N.A.
0
0
N.A.
6.6
93.3
0
13.3
26.6
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
10
10
10
0
10
10
0
0
10
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
10
10
10
0
0
10
10
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
10
0
19
0
28
0
% F
% Gly:
0
10
10
10
0
0
10
0
28
0
37
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
19
10
37
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
10
10
10
19
10
37
10
19
0
% K
% Leu:
0
19
0
37
28
10
19
0
28
0
0
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
28
0
19
0
19
0
0
10
0
0
0
10
0
0
0
% N
% Pro:
0
10
0
19
19
28
28
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
10
10
10
0
10
0
0
0
19
10
% Q
% Arg:
19
37
0
10
10
0
0
19
19
0
19
0
28
0
0
% R
% Ser:
10
0
10
0
0
19
0
37
10
0
0
19
10
0
10
% S
% Thr:
10
0
0
0
0
10
0
0
0
10
19
10
28
19
28
% T
% Val:
0
10
10
10
0
0
10
0
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
19
0
28
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _