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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTR1B
All Species:
12.73
Human Site:
Y40
Identified Species:
28
UniProt:
P28222
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28222
NP_000854.1
390
43568
Y40
C
S
A
K
D
Y
I
Y
Q
D
S
I
S
L
P
Chimpanzee
Pan troglodytes
Q9N2D9
365
41472
G32
L
V
S
L
T
L
S
G
L
A
L
M
T
T
T
Rhesus Macaque
Macaca mulatta
XP_001113679
390
43517
Y40
C
S
T
K
D
Y
I
Y
Q
D
S
I
A
L
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28334
386
43060
Y36
C
S
A
D
G
Y
I
Y
Q
D
S
I
A
L
P
Rat
Rattus norvegicus
P28564
386
43144
Y36
C
S
A
D
D
Y
I
Y
Q
D
S
I
A
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514834
364
39461
S31
A
A
P
S
T
V
H
S
L
Q
I
S
L
A
V
Chicken
Gallus gallus
NP_001166252
379
41857
A33
E
E
G
I
Y
Q
D
A
T
P
L
S
G
K
I
Frog
Xenopus laevis
Q98998
408
45769
A53
F
G
N
A
C
V
I
A
A
I
A
L
E
R
S
Zebra Danio
Brachydanio rerio
NP_001122181
380
42240
D32
V
T
L
T
P
K
T
D
E
K
Q
E
S
F
A
Tiger Blowfish
Takifugu rubipres
O42384
416
47013
L64
A
I
A
L
E
R
S
L
Q
N
V
A
N
Y
L
Fruit Fly
Dros. melanogaster
P20905
564
60843
G153
L
L
E
E
F
A
A
G
E
F
V
L
P
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.6
98.2
N.A.
N.A.
92
92.8
N.A.
56.9
82.8
42.4
64.3
42
28
N.A.
N.A.
N.A.
Protein Similarity:
100
60.5
99.4
N.A.
N.A.
94.3
95.3
N.A.
69.7
89.4
57.8
77.1
59.1
41.4
N.A.
N.A.
N.A.
P-Site Identity:
100
0
86.6
N.A.
N.A.
80
86.6
N.A.
0
0
6.6
6.6
13.3
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
N.A.
N.A.
86.6
93.3
N.A.
6.6
0
20
20
33.3
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
37
10
0
10
10
19
10
10
10
10
28
10
10
% A
% Cys:
37
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
28
0
10
10
0
37
0
0
0
0
0
% D
% Glu:
10
10
10
10
10
0
0
0
19
0
0
10
10
0
0
% E
% Phe:
10
0
0
0
10
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
10
10
0
10
0
0
19
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
0
0
46
0
0
10
10
37
0
0
10
% I
% Lys:
0
0
0
19
0
10
0
0
0
10
0
0
0
10
0
% K
% Leu:
19
10
10
19
0
10
0
10
19
0
19
19
10
37
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% N
% Pro:
0
0
10
0
10
0
0
0
0
10
0
0
10
10
37
% P
% Gln:
0
0
0
0
0
10
0
0
46
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
37
10
10
0
0
19
10
0
0
37
19
19
0
10
% S
% Thr:
0
10
10
10
19
0
10
0
10
0
0
0
10
10
10
% T
% Val:
10
10
0
0
0
19
0
0
0
0
19
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
37
0
37
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _