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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCD3 All Species: 32.42
Human Site: S294 Identified Species: 50.95
UniProt: P28288 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28288 NP_001116146.1 659 75476 S294 R E K Q T V H S V F R K L V E
Chimpanzee Pan troglodytes XP_513575 749 85146 S380 R E K Q T V H S V F R K L V E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537064 628 72271 S280 N F I L F R F S M G F I D S I
Cat Felis silvestris
Mouse Mus musculus P55096 659 75464 S294 R E K Q T I H S V F R K L V E
Rat Rattus norvegicus P16970 659 75297 S294 R E K Q T I H S V F R K L V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511038 639 73467 S274 R E K H T I H S V F R K L V E
Chicken Gallus gallus NP_001012615 660 75516 R296 R E K Q T I H R T F R K L V E
Frog Xenopus laevis NP_001084980 657 75020 S292 R E K L T I Y S S F Q K L V E
Zebra Danio Brachydanio rerio NP_998647 656 74975 S293 R E K Q T I H S T F K K L V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608354 665 75282 A298 R E K L T L L A S Y S K L R S
Honey Bee Apis mellifera XP_624872 664 76900 T298 R E K L I L L T S F H K L I T
Nematode Worm Caenorhab. elegans NP_495408 661 74832 S297 S E K E T I M S T F A S L V Q
Sea Urchin Strong. purpuratus XP_788720 665 76166 K298 P E Q R T I N K T F K K L V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94FB9 1337 149558 Q317 R E E S H I Q Q K F K N L V S
Baker's Yeast Sacchar. cerevisiae P41909 870 100007 E423 V E R T K V K E L Y D V L M E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 N.A. 90.5 N.A. 94.5 95.4 N.A. 90.1 88.4 87.4 82.8 N.A. 58.5 57.8 58.5 67.2
Protein Similarity: 100 85.3 N.A. 92.7 N.A. 97.1 97.5 N.A. 93.7 93.7 93.9 90.7 N.A. 73.8 74.5 75 82.4
P-Site Identity: 100 100 N.A. 6.6 N.A. 93.3 93.3 N.A. 86.6 80 66.6 73.3 N.A. 40 40 46.6 40
P-Site Similarity: 100 100 N.A. 13.3 N.A. 100 100 N.A. 93.3 86.6 86.6 93.3 N.A. 60 60 66.6 80
Percent
Protein Identity: N.A. N.A. N.A. 22.5 25.8 N.A.
Protein Similarity: N.A. N.A. N.A. 35 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 14 % D
% Glu: 0 94 7 7 0 0 0 7 0 0 0 0 0 0 54 % E
% Phe: 0 7 0 0 7 0 7 0 0 80 7 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 7 7 0 47 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 7 0 7 60 0 0 0 0 0 7 0 7 7 % I
% Lys: 0 0 74 0 7 0 7 7 7 0 20 74 0 0 0 % K
% Leu: 0 0 0 27 0 14 14 0 7 0 0 0 94 0 0 % L
% Met: 0 0 0 0 0 0 7 0 7 0 0 0 0 7 0 % M
% Asn: 7 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % N
% Pro: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 40 0 0 7 7 0 0 7 0 0 0 7 % Q
% Arg: 74 0 7 7 0 7 0 7 0 0 40 0 0 7 0 % R
% Ser: 7 0 0 7 0 0 0 60 20 0 7 7 0 7 14 % S
% Thr: 0 0 0 7 74 0 0 7 27 0 0 0 0 0 7 % T
% Val: 7 0 0 0 0 20 0 0 34 0 0 7 0 74 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 14 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _