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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCD3 All Species: 37.58
Human Site: Y545 Identified Species: 59.05
UniProt: P28288 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28288 NP_001116146.1 659 75476 Y545 S D L V L K E Y L D N V Q L G
Chimpanzee Pan troglodytes XP_513575 749 85146 Y631 S D L V L K E Y L D N V Q L G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537064 628 72271 Y514 S D L V L K E Y L D N V Q L G
Cat Felis silvestris
Mouse Mus musculus P55096 659 75464 Y545 S D Q V L K E Y L D N V Q L G
Rat Rattus norvegicus P16970 659 75297 Y545 S D Q V L K G Y L D N V Q L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511038 639 73467 Y525 S D L V L K E Y L D N V Q L G
Chicken Gallus gallus NP_001012615 660 75516 Y546 S D Q V L K E Y L D N V Q L G
Frog Xenopus laevis NP_001084980 657 75020 Y543 S D K V L K E Y L D N V Q L G
Zebra Danio Brachydanio rerio NP_998647 656 74975 Y542 S D L V L K E Y L D N V Q L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608354 665 75282 Y551 S D E D L M H Y L D I V Q L T
Honey Bee Apis mellifera XP_624872 664 76900 K542 M T D I D L K K L L D L V Q L
Nematode Worm Caenorhab. elegans NP_495408 661 74832 M547 S D S D L E Q M L E N V Q L T
Sea Urchin Strong. purpuratus XP_788720 665 76166 M551 T D K D I E E M I E K V Q L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94FB9 1337 149558 L558 E I G M V E L L K N V D L E Y
Baker's Yeast Sacchar. cerevisiae P41909 870 100007 I720 R D K E L V Q I L V E V K L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 N.A. 90.5 N.A. 94.5 95.4 N.A. 90.1 88.4 87.4 82.8 N.A. 58.5 57.8 58.5 67.2
Protein Similarity: 100 85.3 N.A. 92.7 N.A. 97.1 97.5 N.A. 93.7 93.7 93.9 90.7 N.A. 73.8 74.5 75 82.4
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 86.6 N.A. 100 93.3 93.3 100 N.A. 60 6.6 53.3 33.3
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 86.6 N.A. 100 93.3 93.3 100 N.A. 60 33.3 73.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 22.5 25.8 N.A.
Protein Similarity: N.A. N.A. N.A. 35 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 87 7 20 7 0 0 0 0 67 7 7 0 0 7 % D
% Glu: 7 0 7 7 0 20 60 0 0 14 7 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 60 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 7 7 0 0 7 7 0 7 0 0 0 0 % I
% Lys: 0 0 20 0 0 60 7 7 7 0 7 0 7 0 0 % K
% Leu: 0 0 34 0 80 7 7 7 87 7 0 7 7 87 7 % L
% Met: 7 0 0 7 0 7 0 14 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 67 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 20 0 0 0 14 0 0 0 0 0 80 7 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 74 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 14 % T
% Val: 0 0 0 60 7 7 0 0 0 7 7 87 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _