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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX2 All Species: 21.82
Human Site: S221 Identified Species: 36.92
UniProt: P28328 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28328 NP_000309.1 305 34843 S221 Q K L K A K L S S W C I P L T
Chimpanzee Pan troglodytes XP_519817 326 37490 S242 Q K L K A K L S S W C I P L T
Rhesus Macaque Macaca mulatta XP_001089931 253 28601 S169 Q K L K A K L S S W C I P L T
Dog Lupus familis XP_544136 305 35062 S221 Q K L K A K L S S W C I P L T
Cat Felis silvestris
Mouse Mus musculus P55098 305 34713 S221 Q K L K A K L S S W C T L C T
Rat Rattus norvegicus P24392 305 34749 S221 Q K L K A K L S S W C I P L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519317 263 28547 A172 E N G E P T E A P G S R P R S
Chicken Gallus gallus NP_001008454 304 35215 C221 Q K L K L K I C S W C F P I A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648210 281 32351 V188 F M E I L G L V L P I I N F R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202188 340 38906 Q256 A Q P Q S V R Q V T F E F M T
Poplar Tree Populus trichocarpa XP_002299722 341 39134 I258 P L L N S S S I K K F L S P F
Maize Zea mays NP_001131851 337 38302 L253 F S E M L L L L L P L L N S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9CA86 333 38156 L244 N E F S E M L L L L L P L L N
Baker's Yeast Sacchar. cerevisiae P32800 271 30733 Q179 V F A G L E Y Q N R Q L L W N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 80.9 89.8 N.A. 86.8 87.8 N.A. 28.5 73.7 N.A. N.A. N.A. 32.1 N.A. N.A. 33.2
Protein Similarity: 100 88.3 82.6 94.7 N.A. 94 94.7 N.A. 41.3 84.5 N.A. N.A. N.A. 48.5 N.A. N.A. 50.5
P-Site Identity: 100 100 100 100 N.A. 80 100 N.A. 6.6 60 N.A. N.A. N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 80 100 N.A. 33.3 73.3 N.A. N.A. N.A. 13.3 N.A. N.A. 33.3
Percent
Protein Identity: 28.4 27 N.A. 29.4 25.2 N.A.
Protein Similarity: 47.5 48 N.A. 50.7 40 N.A.
P-Site Identity: 6.6 6.6 N.A. 13.3 0 N.A.
P-Site Similarity: 20 20 N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 43 0 0 8 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 50 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 8 15 8 8 8 8 0 0 0 0 8 0 0 0 % E
% Phe: 15 8 8 0 0 0 0 0 0 0 15 8 8 8 8 % F
% Gly: 0 0 8 8 0 8 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 8 0 0 8 43 0 8 0 % I
% Lys: 0 50 0 50 0 50 0 0 8 8 0 0 0 0 0 % K
% Leu: 0 8 58 0 29 8 65 15 22 8 15 22 22 43 0 % L
% Met: 0 8 0 8 0 8 0 0 0 0 0 0 0 8 0 % M
% Asn: 8 8 0 8 0 0 0 0 8 0 0 0 15 0 15 % N
% Pro: 8 0 8 0 8 0 0 0 8 15 0 8 50 8 0 % P
% Gln: 50 8 0 8 0 0 0 15 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 8 0 8 0 8 8 % R
% Ser: 0 8 0 8 15 8 8 43 50 0 8 0 8 8 15 % S
% Thr: 0 0 0 0 0 8 0 0 0 8 0 8 0 0 50 % T
% Val: 8 0 0 0 0 8 0 8 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 50 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _