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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX2
All Species:
21.82
Human Site:
S221
Identified Species:
36.92
UniProt:
P28328
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28328
NP_000309.1
305
34843
S221
Q
K
L
K
A
K
L
S
S
W
C
I
P
L
T
Chimpanzee
Pan troglodytes
XP_519817
326
37490
S242
Q
K
L
K
A
K
L
S
S
W
C
I
P
L
T
Rhesus Macaque
Macaca mulatta
XP_001089931
253
28601
S169
Q
K
L
K
A
K
L
S
S
W
C
I
P
L
T
Dog
Lupus familis
XP_544136
305
35062
S221
Q
K
L
K
A
K
L
S
S
W
C
I
P
L
T
Cat
Felis silvestris
Mouse
Mus musculus
P55098
305
34713
S221
Q
K
L
K
A
K
L
S
S
W
C
T
L
C
T
Rat
Rattus norvegicus
P24392
305
34749
S221
Q
K
L
K
A
K
L
S
S
W
C
I
P
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519317
263
28547
A172
E
N
G
E
P
T
E
A
P
G
S
R
P
R
S
Chicken
Gallus gallus
NP_001008454
304
35215
C221
Q
K
L
K
L
K
I
C
S
W
C
F
P
I
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648210
281
32351
V188
F
M
E
I
L
G
L
V
L
P
I
I
N
F
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202188
340
38906
Q256
A
Q
P
Q
S
V
R
Q
V
T
F
E
F
M
T
Poplar Tree
Populus trichocarpa
XP_002299722
341
39134
I258
P
L
L
N
S
S
S
I
K
K
F
L
S
P
F
Maize
Zea mays
NP_001131851
337
38302
L253
F
S
E
M
L
L
L
L
L
P
L
L
N
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CA86
333
38156
L244
N
E
F
S
E
M
L
L
L
L
L
P
L
L
N
Baker's Yeast
Sacchar. cerevisiae
P32800
271
30733
Q179
V
F
A
G
L
E
Y
Q
N
R
Q
L
L
W
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
80.9
89.8
N.A.
86.8
87.8
N.A.
28.5
73.7
N.A.
N.A.
N.A.
32.1
N.A.
N.A.
33.2
Protein Similarity:
100
88.3
82.6
94.7
N.A.
94
94.7
N.A.
41.3
84.5
N.A.
N.A.
N.A.
48.5
N.A.
N.A.
50.5
P-Site Identity:
100
100
100
100
N.A.
80
100
N.A.
6.6
60
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
80
100
N.A.
33.3
73.3
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
28.4
27
N.A.
29.4
25.2
N.A.
Protein Similarity:
47.5
48
N.A.
50.7
40
N.A.
P-Site Identity:
6.6
6.6
N.A.
13.3
0
N.A.
P-Site Similarity:
20
20
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
43
0
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
50
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
15
8
8
8
8
0
0
0
0
8
0
0
0
% E
% Phe:
15
8
8
0
0
0
0
0
0
0
15
8
8
8
8
% F
% Gly:
0
0
8
8
0
8
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
8
0
0
8
43
0
8
0
% I
% Lys:
0
50
0
50
0
50
0
0
8
8
0
0
0
0
0
% K
% Leu:
0
8
58
0
29
8
65
15
22
8
15
22
22
43
0
% L
% Met:
0
8
0
8
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
8
0
8
0
0
0
0
8
0
0
0
15
0
15
% N
% Pro:
8
0
8
0
8
0
0
0
8
15
0
8
50
8
0
% P
% Gln:
50
8
0
8
0
0
0
15
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
0
8
0
8
8
% R
% Ser:
0
8
0
8
15
8
8
43
50
0
8
0
8
8
15
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
50
% T
% Val:
8
0
0
0
0
8
0
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
50
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _