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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACADL All Species: 41.21
Human Site: Y381 Identified Species: 69.74
UniProt: P28330 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28330 NP_001599.1 430 47656 Y381 E L Q N S V A Y D C V Q L H G
Chimpanzee Pan troglodytes A5A6I0 421 46589 T370 D I A N Q L A T D A V Q I L G
Rhesus Macaque Macaca mulatta XP_001109931 436 48576 Y387 E L Q N S V A Y D C V Q L H G
Dog Lupus familis XP_536053 441 49386 Y392 E L Q N R I A Y D C V Q L H G
Cat Felis silvestris
Mouse Mus musculus P51174 430 47889 Y381 E L Q N S V A Y E C V Q L H G
Rat Rattus norvegicus P15650 430 47854 Y381 E L Q N T V A Y Q C V Q L H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508315 317 34996 H276 A H L Q T V Q H K L A E L K T
Chicken Gallus gallus NP_001006511 431 47871 T382 D L Q N S V A T Q C V Q L H G
Frog Xenopus laevis NP_001086834 444 49256 T395 D L Q N T V A T Q C L Q L H G
Zebra Danio Brachydanio rerio NP_957475 442 49379 T393 D L Q N R V A T Q C L Q L H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSA3 419 45853 S366 D M A N K I A S D A V Q I F G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22347 417 44800 T360 D T A N Q A A T N A V Q I F G
Sea Urchin Strong. purpuratus XP_782503 443 48873 T394 D V I N K V A T E C L Q L H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SWG0 409 44755 L360 E R A T Q V A L Q A I Q C L G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.6 88.5 81.8 N.A. 86.2 85.3 N.A. 61.6 77.4 73.8 70.3 N.A. 31.1 N.A. 29.7 59.3
Protein Similarity: 100 53.2 91.2 87.7 N.A. 93 92.3 N.A. 68.1 86.7 84.6 80.7 N.A. 54.4 N.A. 50.2 72.9
P-Site Identity: 100 40 100 86.6 N.A. 93.3 86.6 N.A. 13.3 80 66.6 66.6 N.A. 40 N.A. 33.3 53.3
P-Site Similarity: 100 66.6 100 93.3 N.A. 100 93.3 N.A. 33.3 86.6 86.6 80 N.A. 66.6 N.A. 53.3 80
Percent
Protein Identity: N.A. N.A. N.A. 30.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 53.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 29 0 0 8 93 0 0 29 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 65 0 0 8 0 0 % C
% Asp: 50 0 0 0 0 0 0 0 36 0 0 0 0 0 0 % D
% Glu: 43 0 0 0 0 0 0 0 15 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93 % G
% His: 0 8 0 0 0 0 0 8 0 0 0 0 0 65 0 % H
% Ile: 0 8 8 0 0 15 0 0 0 0 8 0 22 0 0 % I
% Lys: 0 0 0 0 15 0 0 0 8 0 0 0 0 8 0 % K
% Leu: 0 58 8 0 0 8 0 8 0 8 22 0 72 15 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 86 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 58 8 22 0 8 0 36 0 0 93 0 0 0 % Q
% Arg: 0 8 0 0 15 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 29 0 0 8 0 0 0 0 0 0 0 % S
% Thr: 0 8 0 8 22 0 0 43 0 0 0 0 0 0 8 % T
% Val: 0 8 0 0 0 72 0 0 0 0 65 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _